Anua PDRN Hyaluronic Acid Capsule 100 Serum Mask sachet
Good choice for Dehydration
What makes this different

Where most PDRN masks are cotton or tencel sheets soaked in a watery essence, this is a true hydrogel that carries a 23 mL serum with eight different hyaluronate weights, a high placement of niacinamide, trehalose and the salmon-DNA PDRN of Anua's Capsule 100 serum line, and it clings closely enough to be worn overnight. It is effectively the Capsule 100 serum delivered as a twenty-minute occlusive soak.

Anua

Anua PDRN Hyaluronic Acid Capsule 100 Serum Mask Review

Hydrogel Glow Sheet Masks sheet-mask k beauty Paraben free Cruelty free

A superb hydration mask sold under a slightly grander name than it needs. The hydrogel clings, the 23 mL serum carries eight hyaluronate weights and a real dose of niacinamide, and skin is visibly plumper and dewier for a day. The salmon PDRN is a humectant here, not a repair treatment, and the glow is temporary by design. At about two dollars a sheet it is a fair, fragrance-free daily indulgence.

Price $24.00 10 sheets (23 mL each) · more sizes
Shopper rating 4.9 ★★★★★ 36 reviews
On the market 2025 Made in South Korea
Buy at Amazon ♥
Verdicts

How well it fits each concern

Fewer than forty reviews sit on Anua's US site and Ulta for this mask since its 2025 arrival, so the judgement here comes mostly from the ingredient list, the brand's own one-use hydration measurements and the well-understood behaviour of layered hyaluronic hydrogel masks. Long-run feedback on the sheet's fit across face shapes and on the botanicals' tolerability for reactive skin is still thin.

One verdict per concern. Open a row for the reasoning; the receipt has every source.

The scaleRecommendedGoodSupportingEarly evidenceNot for thisAvoidhow it works

Good choicefor DehydrationHyaluronic Acid is a reference standard by mechanism for dehydration; this sheet mask carries it.Receipt1 source on the row · concentration not declared; studied range 0.1% · row checked Jul 17, 2026 · rule R5, same reading on 9,843 products · open the receipt

The case for it

  1. Hyaluronic Acid Complex is a reference standard by mechanism for this concern — an established physical action, not a trial result.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries none of the triggers this concern is sensitive to.

Limited evidenceGentleNo reviews read yet

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Good choice” is the verdict on 10,340 of 45,446 concern verdicts across the catalog; rule R5 decided 9,843 of them. Unchanged since September 25, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All dehydration products →

Unprovenfor DullnessHyaluronic Acid has early or mechanistic evidence for dullness — a reasonable bet, not a recommendation; the other actives here are not yet assessed for it.Receipt1 source on the row · row checked Jul 17, 2026 · rule R9, same reading on 4,156 products · open the receipt

The case for it

  1. Hyaluronic Acid Complex has early or mechanistic evidence for this concern, not trial-backed standing.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries none of the triggers this concern is sensitive to.

Limited evidenceGentleNo reviews read yet

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Unproven” is the verdict on 4,156 of 45,446 concern verdicts across the catalog; rule R9 decided 4,156 of them. Unchanged since October 9, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All dullness products →How dullness is treated →

Good choicefor DrynessHyaluronic Acid is a reference standard by mechanism for dryness; this sheet mask carries it.Receipt2 sources on the row · rule R5, same reading on 9,843 products · open the receipt

The case for it

  1. Hyaluronic Acid Complex is a reference standard by mechanism for this concern — an established physical action, not a trial result.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries none of the triggers this concern is sensitive to.

Limited evidenceGentleNo reviews read yet

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Good choice” is the verdict on 10,340 of 45,446 concern verdicts across the catalog; rule R5 decided 9,843 of them. As of October 13, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All dryness products →

As a maskNot judged: what a mask is for — works within its wear time, benefit outlasts the mask, comes off cleanly — cannot yet be measured from the ingredient list (only intensity without injury can).

A verdict is Dermington’s assessment of how well a product’s ingredients fit a concern — never a claim about what the product treats. Evidence dots and collected reviews sit beside it and are never blended in. Rules 0.5.1 · evidence table ev-2026.10-r231 · engine 5.2.0 · how we decide · this product’s receipt

Reader poll · Town SquareQuestion 1 of up to 3

Have you used PDRN Hyaluronic Acid Capsule 100 Serum Mask?

One tap counts. A couple of optional follow-ups come next.

No account neededOne answer each, change it any timeCounted only in anonymous totalsHow the Square counts →
Assessment

Pros & cons

What it does well 7

  • Ultra-thin hydrogel clings to facial contours without sliding during wear
  • Niacinamide placed fourth gives real follow-through beyond the day-long plumping
  • Eight hyaluronate weights and trehalose deliver visible dewiness after one use
  • Fragrance-free, alcohol-free and acid-free, so reactive skin can usually wear it
  • Generous 23 mL serum load leaves enough to pat into neck and hands
  • Allantoin and panthenol make it a soothing choice after retinoid nights
  • Anua discloses its one-use hydration measurements rather than vague claims

Where it falls short 6

  • PDRN and collagen act as humectants here, not the repair actives the name implies
  • Glow is temporary and fades within about a day, like any hydration mask
  • Leftover serum is tacky, and oily skin may find the finish too glossy
  • Daily use as the brand suggests becomes expensive quickly
  • Neem, turmeric and holy basil extracts may bother botanically sensitive skin
  • Two-piece sheet takes a moment to position and the backing film can tear
Review

The full review

Salmon DNA has had a strange couple of years. Polydeoxyribonucleotide, PDRN to its fans, went from a wound-healing injectable used by Korean and Italian clinics to the most-hyped ingredient in K-beauty, and along the way it acquired a mythology about skin regeneration that no serum on a shelf could possibly live up to. A sheet mask is the honest end of that trend. Nobody wears a hydrogel for twenty minutes expecting their dermis to rebuild itself. They expect to peel it off and look dewy, and that is a claim a mask can actually be held to. So the fair question about Anua's PDRN Capsule 100 Serum Mask is not whether the salmon DNA works but whether the mask does, and the answer is that it hydrates about as well as any sheet mask sold in the United States.

Start with the sheet, because that is where hydrogel masks are won or lost. This one is a genuinely thin, translucent water-gel in two pieces on a backing film, and it clings. It does not slide down the cheeks when you sit up, it settles into the sides of the nose, and it stays cool for the first ten minutes in a way cotton sheets never manage. Anua calls it seamless adhesion and for once the marketing phrase describes the experience. Twenty-three millilitres of serum is a generous load, and the gel releases it steadily rather than all at once, which is why the twenty-minute wear feels like a soak rather than a rinse.

The serum is where the formula earns its keep. The first four ingredients are water, butylene glycol, glycerin and niacinamide, and that fourth placement matters: most sheet masks bury niacinamide in the tail, whereas here it is plausibly at the two-to-five percent range that the barrier and tone research used. Trehalose sits seventh as a second humectant. Then, spread through the back half of the list, come eight forms of hyaluronate, from a surface-sitting crosspolymer to hydrolysed fragments that reach the upper layers of the epidermis, plus hydrolysed collagen, allantoin, panthenol and adenosine. The PDRN itself, listed as sodium DNA, sits nineteenth, behind the first of the hyaluronic acids. That placement is honest. It is present, it is soothing, it binds water, and it is not the engine.

The effect is immediate and pleasant. Skin comes out of the mask visibly plumper, with the slight tackiness of the leftover serum that, once patted in and sealed with a moisturiser, sets into the glassy, light-catching finish the brand is selling. It lasts through the next morning. Anua's own instrumental test reports deep hydration up about twenty-eight percent and surface plumping up about eight percent after a single use, and while those are in-house numbers with the usual caveats, they describe a one-use effect that anyone can see in a mirror, and they are notably not claims about firming or wrinkles. The formula is fragrance-free, alcohol-free, acid-free and free of essential oils, which makes it one of the few hydrogels that reactive and rosacea-prone skin can usually wear without a sting.

What it will not do is anything permanent from a single sheet, and the name invites a little confusion on that point. Hydrolysed collagen on the skin is a film-forming humectant; it does not add collagen. PDRN on the skin is a soothing polymer; it does not regenerate tissue. Used every day or two for a month, the niacinamide and the steady hydration do add up to a more even, less dull complexion, and that is a real benefit, but it is a niacinamide benefit that a good serum would deliver more cheaply. Oily skin may find the finish a touch too glossy for morning use, and the botanical extracts near the middle of the list, neem, turmeric, holy basil, are the only plausible triggers for anyone with plant sensitivities.

On price, twenty-four dollars for ten sheets at Ulta works out to two dollars and forty cents a mask, which is mid-range for a K-beauty hydrogel and reasonable given the serum volume and the sheet quality. Anua's own site periodically bundles two boxes at a discount, which brings the per-sheet cost under a dollar and a half. Used daily, as the brand suggests, the habit costs seventy dollars a month, which is where the value argument frays; used two or three times a week, or as a recovery step after retinoid nights or a flight, the box lasts a couple of months and the maths is comfortable.

Anua is a six-year-old brand that has grown at a speed few K-beauty labels have matched, and it deserves credit for disclosing its test results and building formulas that are consistently gentle. It does not yet have independent clinical work on individual products, and the PDRN story is a trend it is riding rather than one it invented. None of that changes what the mask does. For dehydrated, dull or tired skin that wants a reliable overnight-visible glow without fragrance or acids, this is a very good sheet mask and a mildly overdressed one. Buy it for the hydrogel and the hyaluronic acids, enjoy the salmon as a bonus, and do not expect it to do more than a mask can.

The science

The measurable effects of this mask come from occlusion and humectancy, and the formula is unusually well built for both. A hydrogel sheet traps water against the stratum corneum for the duration of the wear, temporarily raising corneocyte hydration and flattening fine dehydration lines; that alone accounts for much of the plumping any sheet mask produces. What distinguishes this serum is the layering of hyaluronates by molecular weight. High-molecular-weight sodium hyaluronate and a hyaluronate crosspolymer form a water-holding film on the surface, while hydrolysed and low-weight fragments have been shown in ex vivo skin models to reach the upper epidermis and improve hydration measured by corneometry for several hours after application. Eight forms are listed, which is more for marketing than mechanism, but the spread of sizes is what produces the combination of immediate surface plumping and a next-morning effect that a single-weight hyaluronic acid would not.

Niacinamide, placed fourth, is the ingredient with the strongest evidence for benefit beyond a day. Controlled trials of topical niacinamide at two to five percent over eight to twelve weeks show increased ceramide synthesis, reduced transepidermal water loss and a modest reduction in hyperpigmentation, and a daily mask is a plausible if expensive way to deliver it. Trehalose, a disaccharide, protects proteins and membranes against dehydration stress and is well documented as a humectant; placed ahead of the hyaluronic acids, it also guards against the reverse-osmosis drying that can occur when a gel sheet is worn too long.

The PDRN, listed as sodium DNA, is the ingredient whose evidence is most often misapplied. Polydeoxyribonucleotide has a genuine literature in wound healing and tissue repair through adenosine A2A receptor activation, but that evidence comes from injected and topical wound-care use on damaged tissue, not from short-contact cosmetic application on intact skin. On a sheet mask it functions as a large, hydrophilic, film-forming polymer with some anti-inflammatory activity; no controlled study shows topical cosmetic PDRN regenerating skin. Hydrolysed collagen is likewise a surface humectant, since intact collagen cannot cross the stratum corneum. Anua's reported one-use improvements in deep hydration and plumping come from a brand-commissioned test at a Korean dermatological testing institute on twenty-two women aged 44 to 68, measured ten minutes after a single application; they are consistent with the humectant-and-occlusion mechanism and describe a temporary effect, not independent evidence of lasting benefit.

The clinical view

Hydrating sheet masks sit in the category dermatologists tend to describe as harmless and pleasant: they raise skin hydration for a day, they can be a useful soothing step during retinoid adjustment or after a procedure, and they do not change the structure of the skin. Clinicians who have looked at the PDRN trend are generally careful to separate the injectable and wound-care evidence for polydeoxyribonucleotide, which is real, from the cosmetic claims made for it on sheets and serums, which are not supported by controlled studies. Read that way, this mask is well regarded for what it is: a fragrance-free, alcohol-free hydrogel with a meaningful niacinamide placement and layered hyaluronic acids, appropriate for dry, dehydrated and sensitive skin, and reasonable to use after tretinoin nights as a buffer. Standard cautions are minor. Patients with a history of reacting to botanical extracts are told to patch test, people prone to Malassezia folliculitis are reminded that daily occlusion with a serum-heavy mask can aggravate it, and nobody is told to expect firming. For persistent dryness, eczema or rosacea a mask is a supplement to treatment, not a substitute for it.

Formula

Key ingredients

  1. Sodium DNA (PDRN)

    The salmon-derived DNA fragments that give the Capsule 100 line its name, listed nineteenth here behind the humectants that make up most of the serum. On a twenty-minute sheet mask the PDRN's studied regenerative role in injected form does not translate; what it contributes is a soothing, water-binding polymer that helps the gel sheet hold a dense reservoir of serum against the skin.

    Not yet assessed
  2. Niacinamide

    Fourth on the list, which is a higher placement than most hydration masks give it and likely puts it at a working concentration. Its job in this formula is the follow-through: while the hyaluronic acids plump for a day, the niacinamide from a run of masks gives the barrier and tone improvements that make daily use of a serum mask more than a temporary glow.

    Not yet assessed
  3. Hyaluronic Acid Complex (8 forms)

    Eight molecular sizes of hyaluronate, from a crosspolymer that sits on the surface to hydrolysed fragments that reach the upper epidermis, spread through the back half of the list. The staggered sizes are what create the measurable one-use plumping the brand reports, with the large forms holding water on the surface and the small ones pulling it a little deeper for a few hours.

    Established mechanism for Dehydration · established mechanism
  4. Hydrolyzed Collagen

    Collagen peptides that act as a film-forming humectant on the skin surface rather than as any kind of collagen replacement. In this mask it thickens the feel of the serum and leaves the slightly tacky, dewy finish that reads as glass skin once the sheet comes off.

    Not yet assessed
  5. Trehalose

    A sugar humectant placed seventh, ahead of any of the hyaluronic acids, which protects the skin surface from drying out as the water in the gel sheet evaporates during a long wear and makes it safe to leave the mask on past the usual twenty minutes.

    Not yet assessed
Full ingredient list 46 ingredients ShowHide

Water, Butylene Glycol, Glycerin, Niacinamide, 1,2-Hexanediol, Isopentyldiol, Trehalose, Carbomer, Arginine, Propanediol, Allantoin, Panthenol, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Xanthan Gum, Adenosine, Melia Azadirachta Leaf Extract, Hydrolyzed Hyaluronic Acid, Sodium DNA, Melia Azadirachta Flower Extract, Disodium EDTA, Glyceryl Acrylate/Acrylic Acid Copolymer, Coccinia Indica Fruit Extract, Solanum Melongena (Eggplant) Fruit Extract, Glyceryl Oleate, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Hydrogenated Lecithin, Ocimum Sanctum Leaf Extract, Hydrolyzed Collagen, Sodium Hyaluronate, Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Coptis Japonica Root Extract, Glutathione, Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Citric Acid, Sodium Citrate, Pentylene Glycol, Sodium Acetylated Hyaluronate

Safety & formulation facts

  • Pregnancy safe
  • Fragrance free
  • Alcohol free
  • Oil free
  • Silicone free
  • Paraben free
  • Sulfate free
  • Cruelty free
  • Not vegan
  • Not fungal-acne safe
Compatibility

Skin types & routine

Routine step treatment
Time of day Night
Best season All year
Finish dewy, glowy

Layering

Apply after cleansing and toner, wear twenty minutes, then pat the leftover serum in and seal it with moisturiser rather than rinsing; on very dry nights the sheet can be left on overnight, though the hydrogel will dry down and lift at the edges.

When to expect results

Plumper, dewier skin within minutes of removing the sheet, lasting through the next morning. With a mask every day or two for a month, the niacinamide and steady hydration produce a more even, less dull complexion; there is no lasting firming effect from a single-use mask.

Pairs well with Hydrating toner beforehandCeramide moisturiser to sealRetinoid nights as a buffer the following evening

A routine built around it

Morning

  1. Gentle cleanser
  2. Hydrating toner
  3. Moisturiser
  4. Sunscreen

Night

  1. Cleansing oil
  2. Gel cleanser
  3. Toner
  4. Anua PDRN Hyaluronic Acid Capsule 100 Serum Maskthis product
  5. Moisturiser
Guidance

How to use it, and who it's for

How to use

Cleanse and apply your usual toner, then open the sachet and lift out the two-piece hydrogel with its backing film. Position the upper piece over the forehead and eyes and the lower piece over the mouth and chin, smoothing each into the contours of the nose and cheeks before peeling off the backing. Relax for ten to twenty minutes, ideally lying back so the gel stays flush. Remove the sheet, pour the serum left in the sachet into your palms and pat it into the face, neck and backs of the hands, then follow with a moisturiser to seal it in; do not rinse. Use up to daily, or two to three times a week for a more economical routine, and store the sachets in the fridge in summer for a cooling, de-puffing effect. Discard the sheet after a single use.

Is it worth the price?

At $24 for ten sheets at Ulta the mask costs about $2.40 a wear, which is mid-pack for a K-beauty hydrogel and fair for a 23 mL serum on a sheet this well made; Anua's own site periodically sells a twenty-sheet double box at a discount that brings the per-mask cost well under two dollars. The value question is frequency. Daily use, which the brand suggests for glass skin, runs to roughly seventy dollars a month for a benefit that a niacinamide serum and a good moisturiser would largely replicate, whereas two or three masks a week as a recovery or pre-event step makes the box last two months and the cost easy to justify. Anua is an established, fast-growing brand that discloses its instrumental tests, and the price reflects a genuinely good hydrogel rather than trend inflation.

Who should buy it

Dry, dehydrated or dull skin that wants a fragrance-free, acid-free mask with a visible next-morning glow, and anyone who needs a gentle soothing step after retinoid nights, flights or a day in the sun. It also suits sensitive skin that finds most hydrogels sting.

Who should skip it

People hoping for the regenerative effects of PDRN injections, since a sheet mask cannot provide them, and oily skin that dislikes a glossy, tacky finish. Vegans should note the salmon DNA and animal collagen, and anyone prone to fungal acne should limit daily occlusive masking.

Ready to try it?Anua PDRN Hyaluronic Acid Capsule 100 Serum Mask · $24.00 · 10 sheets (23 mL each)
Details

The product, in detail

Texture
An ultra-thin, translucent water-gel sheet loaded with a clear, slippery serum that is thicker than a toner and leaves a faintly tacky, glossy layer once patted in.
Scent
Fragrance-free with a faint sweet, slightly herbal note from the neem and turmeric extracts that disappears as the serum absorbs.
Packaging
Individual foil sachets in Anua's pale-blue PDRN livery, sold as a ten-sheet box in the US; each sachet holds 23 mL of serum around a two-piece hydrogel sheet on a backing film.
How long it lasts
A ten-sheet box lasts ten to twenty days used daily as Anua suggests, or two to three months as a twice-weekly treat.
Once opened
Use within 12 months · track your toss-by date →
Size
10 sheets (23 mL each) · other sizes available
Made in
South Korea
Launched
2025

What the first two weeks feel like

The hydrogel is cooler and heavier than a cotton sheet and clings without slipping, and the first minute brings a faint tightening as it settles. Skin is noticeably plumper on removal and stays dewy through the next morning; no tingling, purging or adjustment period is expected from a formula without acids or fragrance.

The story behind it

Why it exists

Anua's PDRN Hyaluronic Acid Capsule 100 serum became the brand's headline product in 2025 on the back of the salmon-DNA trend, and the serum mask followed the same year as the line's sheet-mask extension, arriving at Ulta in 2025 in a ten-count box. It sits in the pale-blue PDRN family alongside the toner, glow pads and moisturising cream.

About Anua Established Brand (5–20 years)

Anua was launched in 2019 by the Korean incubator The Founders and grew into one of the best-selling K-beauty brands in the US, entering Ulta in 2025 on the strength of its heartleaf and PDRN lines. Its products win Olive Young and Hwahae consumer awards and it publishes in-house instrumental tests, but independent clinical validation of individual formulas is not yet available.

Brand founded 2019 · This product since 2025

Myth vs. reality

What people get wrong about it

MythThe PDRN in this mask repairs skin the way PDRN injections do.

RealityThe regenerative evidence for polydeoxyribonucleotide comes from injected and wound-care use, where it reaches living tissue. Sodium DNA on a sheet mask sits on the surface as a soothing, water-binding polymer; the plumping you see is the hyaluronic acid and the occlusive gel, not tissue repair.

MythLeaving the mask on overnight gives more benefit than twenty minutes.

RealityOnce the hydrogel has released its serum and started to dry, it can begin drawing moisture back out of the skin at the edges. Twenty minutes followed by patting in the serum and sealing with a moisturiser captures the benefit; overnight wear is comfortable but not more effective.

FAQ

Questions people ask

How long should I leave the Anua PDRN Capsule 100 serum mask on?

Ten to twenty minutes is the sweet spot; that is when the hydrogel has released most of its serum and before it starts drying at the edges. Pat the leftover serum in afterwards and follow with moisturiser rather than rinsing.

Is the Anua PDRN serum mask the same formula as the Capsule 100 serum?

No. The mask carries a serum built on the same PDRN and hyaluronic acid ideas, with niacinamide placed fourth and eight hyaluronate forms, but it is a different, lighter formula designed to soak in from a hydrogel sheet rather than to be layered daily from a bottle.

Can I use the Anua PDRN sheet mask every day?

Yes. It is fragrance-free, alcohol-free and acid-free, and Anua positions it for daily use. Most people find every other day gives the same glow at half the cost, since the hydration effect of any single mask lasts about a day.

Is the PDRN Capsule 100 mask suitable for sensitive or rosacea-prone skin?

Generally, yes. With no fragrance, alcohol, essential oils or exfoliating acids, and with allantoin, panthenol and trehalose in the formula, it is one of the gentler hydrogel masks available. Patch test on the jawline if you react to botanical extracts, since it contains neem, turmeric and holy basil.

Is the Anua PDRN serum mask vegan?

No. The PDRN is sodium DNA derived from salmon, and the hydrolyzed collagen is animal-derived, so the mask is not suitable for a vegan routine.

Does the Anua PDRN mask help with wrinkles or firming?

It plumps fine dehydration lines for a day through the hyaluronic acids and adds a small amount of adenosine, but a sheet mask does not produce lasting firming. Consistent niacinamide and a retinoid are what change texture over months.

Reviews

What shoppers tend to say

Recurring themes our editors read across retailer reviews — summaries in our words, not quotations, and not a substitute for a patch test.

Common praise

  • Early feedback singles out the thin, clinging hydrogel that does not slide
  • Visible plumping and dewiness the morning after
  • No sting or fragrance on sensitive skin

Common complaints

  • Too few reviews to establish patterns; some early users find the leftover serum tacky
  • Glow fades within a day, as with any hydration mask
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