Ishizawa Lab Acne Barrier Medicated Protect Face Wash 100 g tube
Supporting role for Acne
What makes this different

Unlike Western acne washes built on salicylic acid or benzoyl peroxide, this Japanese quasi-drug relies on dipotassium glycyrrhizate, an anti-inflammatory licorice derivative, in a soap-plus-amino-acid foam scented only with tea tree, lavender, rosemary and eucalyptus oils.

Ishizawa Lab

Ishizawa Lab Acne Barrier Medicated Protect Face Wash Review

Licorice-Active Japanese Acne Wash Cleansers foam j beauty Paraben free Vegan Not cruelty free

A Japanese medicated face wash that treats adult acne the Japanese way: with an anti-inflammatory licorice active rather than an exfoliant. The soap-plus-amino-acid foam cleans oily skin well without over-stripping, but it will not unclog pores like salicylic acid, and its four essential oils make it a poor fit for sensitive or rosacea-prone skin.

Price $24.00 100 g
Buy at Amazon ♥
Verdicts

How well it fits each concern

The official ingredient list follows the Japanese quasi-drug format, which lists the active first and does not show concentration order, and the active's percentage is not disclosed. English-language reviews are limited, so the assessment leans on the formula and on established evidence for its ingredients.

One verdict per concern. Open a row for the reasoning; the receipt has every source.

The scaleRecommendedGoodSupportingEarly evidenceNot for thisAvoidhow it works

Supporting rolefor AcneNothing here targets acne directly; gentle cleansing that does not strip is the recognised companion to treating it, and this foam does that without known triggers.ReceiptDipotassium Glycyrrhizate: no evidence row for this concern yet · rule R8, same reading on 3,793 products · open the receipt

The case for it

  1. Dipotassium Glycyrrhizate has no evidence row yet for this concern — it is in the research queue.
  2. The formula carries no trigger this concern is sensitive to, with the cautions noted.

Not from a trial rowStandard tolerabilityNo reviews read yet

Cautions: fragrance; known irritants; fungal-acne triggers.

What would change this: A researched evidence row for the lead active would replace this with a verdict.

Same rule for everyone. “Supporting role” is the verdict on 7,796 of 45,446 concern verdicts across the catalog; rule R8 decided 3,793 of them. Unchanged since September 25, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All acne products →How acne is treated →

Supporting rolefor Excess OilinessNothing here targets excess oiliness directly; sebum removal without stripping is the recognised companion to treating it, and this foam does that without known triggers.ReceiptDipotassium Glycyrrhizate: no evidence row for this concern yet · rule R8, same reading on 3,793 products · open the receipt

The case for it

  1. Dipotassium Glycyrrhizate has no evidence row yet for this concern — it is in the research queue.
  2. The formula carries no trigger this concern is sensitive to, with the cautions noted.

Not from a trial rowStandard tolerabilityNo reviews read yet

Cautions: fungal-acne triggers.

What would change this: A researched evidence row for the lead active would replace this with a verdict.

Same rule for everyone. “Supporting role” is the verdict on 7,796 of 45,446 concern verdicts across the catalog; rule R8 decided 3,793 of them. Unchanged since September 25, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All excess oiliness products →

Does the jobDoes what a cleanser is for: puts something back, surfactant mildness. Not measured from the label: pH match to skin.

A verdict is Dermington’s assessment of how well a product’s ingredients fit a concern — never a claim about what the product treats. Evidence dots and collected reviews sit beside it and are never blended in. Rules 0.5.1 · evidence table ev-2026.10-r231 · engine 5.2.0 · how we decide · this product’s receipt

Reader poll · Town SquareQuestion 1 of up to 3

Have you used Acne Barrier Medicated Protect Face Wash?

One tap counts. A couple of optional follow-ups come next.

No account neededOne answer each, change it any timeCounted only in anonymous totalsHow the Square counts →
Assessment

Pros & cons

What it does well 6

  • Declared anti-inflammatory active suited to adult acne
  • Soap base softened with an amino-acid surfactant
  • Dense, springy foam from a small amount
  • No added perfume, colourant-free, alcohol-free
  • Glycerin, sorbitol and allantoin add comfort
  • Designed to pair with the rest of the Acne Barrier line

Where it falls short 5

  • Does not exfoliate or unclog pores
  • Four essential oils can irritate sensitive skin
  • Soap base may dry out dry skin
  • Expensive when imported outside Japan
  • Ingredient list is not in concentration order and omits water
Review

The full review

In the United States, an acne face wash almost always means salicylic acid or benzoyl peroxide, the two actives recognised in the over-the-counter acne monograph. In Japan, the category works differently. Medicated products, known as quasi-drugs, must declare an approved active for their claim, and for acne and rough skin one of the most common is dipotassium glycyrrhizate, an anti-inflammatory derived from licorice root. The Ishizawa Lab Acne Barrier Medicated Protect Face Wash follows that model. Its active calms rather than exfoliates, which says a lot about how it should be used and who it will suit.

Ishizawa Laboratories publishes the full ingredient list on its Japanese website, in the format used for quasi-drugs: the active first, followed by other ingredients grouped by purpose rather than strictly by concentration, and without listing water. After dipotassium glycyrrhizate come four essential oils, tea tree, lavender, rosemary and eucalyptus, then sodium copper chlorophyllin, a green colourant with skin-conditioning claims. The cleansing base is a potassium soap made from myristic and stearic acids, softened by sodium lauroyl glutamate, an amino-acid surfactant, and a fatty-acid diethanolamide that builds foam. Glycerin, butylene glycol, sorbitol and allantoin add moisture and comfort.

In use, a small amount whips into a dense, springy foam, which is how Japanese face washes are designed to be used: the foam cushions the skin and does the cleaning, so rubbing is unnecessary. It rinses clean and leaves oily skin feeling fresh and slightly matte, with less tightness than a plain soap. The herbal scent is noticeable; the brand advertises the wash as free from added fragrance, which is accurate, but essential oils are aromatic and can still irritate.

The active deserves a fair assessment. Dipotassium glycyrrhizate has well-documented anti-inflammatory activity in laboratory studies and is widely used in Japanese and Korean skincare to reduce redness and irritation. For adult acne, which often combines inflamed spots with sensitive, irritated skin, a calming active in the cleanser is a reasonable idea. But it does not exfoliate inside pores, and in a wash that is rinsed off after a minute, its contact time is brief. It is best seen as a gentle supporting step, not a treatment that clears clogged pores or kills acne bacteria.

The tea tree oil carries the line's identity. Tea tree has real clinical evidence in acne, but mainly as a five percent gel left on the skin. In a rinse-off at an undisclosed level, its effect is limited, and together with lavender, rosemary and eucalyptus, it adds allergen potential. Essential oils are among the more common causes of contact dermatitis, and people with sensitive skin, rosacea or eczema are better served by an unscented cleanser.

For oily and combination skin with occasional adult breakouts, the wash works well as part of a routine. Pair it with a leave-on active, such as benzoyl peroxide, adapalene or azelaic acid, which does the clearing, while the wash cleans gently and calms. Ishizawa Lab designs the Acne Barrier range to be used together, with a medicated lotion, gel cream and spot essence built on the same licorice active.

Dry skin may find the soap base a little stripping over time, particularly in winter. Using it once daily, in the evening, and rinsing with water in the morning can help. Fungal-acne-prone skin should note the fatty acids.

The foaming technique deserves more attention than it usually gets. Japanese face washes are formulated to be whipped into a stiff foam, ideally with a foaming net, before they touch the skin. That foam acts as a buffer: it lifts oil and dirt while the fingers barely touch the face, which is exactly what inflamed, acne-prone skin needs. Rubbing a thin lather across spots with the fingertips undoes much of that benefit and can make redness worse. With this wash, a coin-sized dollop turned into a palm-full of foam is the right starting point.

It is also worth separating this wash from the brand's men's version, which is sold under a different name with its own formula and packaging. The standard Acne Barrier wash reviewed here is the white tube with a red label marketed for adult acne on combination skin.

On value, the wash is inexpensive in Japanese drugstores, but import pricing is much higher: Japanese Taste sells the 100 gram tube for about twenty-four dollars. That makes it a specialty purchase outside Japan rather than an everyday bargain, although a little foam goes a long way, and a tube lasts six to eight weeks.

Ishizawa Lab, founded in 1996, is a familiar name in Japanese drugstores, known for lines such as Keana Nadeshiko and Toumei Shirohada. The Acne Barrier range has a long track record in Japan, though independent clinical studies of individual products are not published.

The bottom line: a pleasant, well-foaming cleanser that takes a calming approach to adult acne. It is a good match for oily, resilient skin that wants a gentle wash alongside real acne treatments, and a poor match for anyone expecting it to unclog pores or for skin that reacts to essential oils.

The science

Dipotassium glycyrrhizate is the dipotassium salt of glycyrrhizic acid from licorice root. It is approved in Japan as an active ingredient in quasi-drugs for preventing rough skin and acne, and laboratory studies show it inhibits inflammatory mediators, including those involved in redness and swelling. Clinical data specific to acne are limited, and its effect in a rinse-off product is constrained by short contact time. Its role is best understood as anti-inflammatory support rather than comedolytic or antibacterial treatment.

The cleansing system combines a potassium soap, formed from myristic and stearic acids with potassium hydroxide, with sodium lauroyl glutamate, an amino-acid-based surfactant known for mildness. Blending a mild surfactant into a soap base reduces the alkaline, lipid-stripping effect of soap alone, which is associated with increased transepidermal water loss and tightness. Glycerin and sorbitol add humectancy.

Melaleuca alternifolia (tea tree) oil has randomised trial evidence in mild to moderate acne when applied as a 5 percent gel, with slower but better-tolerated results than benzoyl peroxide in an early study. In a cleanser, contact time and concentration are both much lower. Lavender, rosemary and eucalyptus oils contain terpenes such as linalool, limonene and 1,8-cineole, which can oxidise into allergens and are recognised contributors to fragrance contact allergy.

Sodium copper chlorophyllin, a water-soluble chlorophyll derivative, has been studied for its antioxidant properties and in small trials on photodamaged skin, though evidence in cleansers is minimal.

The clinical view

Dermatologists generally recommend a gentle cleanser for acne-prone skin, with treatment coming from leave-on agents such as benzoyl peroxide, retinoids, azelaic acid or salicylic acid. Anti-inflammatory ingredients like licorice derivatives can help calm irritated, breakout-prone skin, particularly in adults. Soap-based cleansers may be too drying for patients using retinoids or those with sensitive skin, and essential oils are a known source of contact allergy. Clinicians often suggest fragrance-free and essential-oil-free products for patients with rosacea, eczema or sensitive skin. Persistent or scarring acne warrants medical treatment.

Formula

Key ingredients

  1. Dipotassium Glycyrrhizate

    The registered active of this Japanese quasi-drug, an anti-inflammatory licorice derivative meant to calm the redness of adult breakouts rather than unclog pores.

    Not yet assessed
  2. Melaleuca Alternifolia (Tea Tree) Leaf Oil

    The signature essential oil of the Acne Barrier line, joined by lavender, rosemary and eucalyptus oils; in a rinse-off it contributes more scent and tradition than measurable antibacterial action.

    Not yet assessed
  3. Sodium Lauroyl Glutamate

    An amino-acid surfactant added to the potassium soap base to make the foam milder and less stripping.

    Not yet assessed
  4. Myristic Acid

    With stearic acid and potassium hydroxide, forms the plant-origin soap that produces the firm, creamy foam.

    Not yet assessed
  5. Glycerin

    Supports the brand's promise to leave moisture behind, alongside butylene glycol, sorbitol and allantoin.

    Not yet assessed
Full ingredient list 17 ingredients ShowHide

Active ingredient: Dipotassium Glycyrrhizate. Other ingredients: Melaleuca Alternifolia (Tea Tree) Leaf Oil, Lavandula Angustifolia (Lavender) Oil, Rosmarinus Officinalis (Rosemary) Leaf Oil, Eucalyptus Globulus Leaf Oil, Sodium Copper Chlorophyllin, Glycerin, Butylene Glycol, Allantoin, Myristic Acid, Stearic Acid, Glyceryl Stearate SE, Lauric/Myristic Acid Diethanolamide, Sodium Lauroyl Glutamate, Potassium Hydroxide, Sorbitol, Pentasodium Pentetate, Phenoxyethanol

Safety & formulation facts

  • Pregnancy safe
  • Not fragrance free
  • Alcohol free
  • Not oil free
  • Silicone free
  • Paraben free
  • Sulfate free
  • Not cruelty free
  • Vegan
  • Not fungal-acne safe
Pore-clogging (comedogenic) Myristic Acid
Potential irritants Potassium soap baseEssential oils (tea tree, lavender, rosemary, eucalyptus)
Common allergens Melaleuca Alternifolia (Tea Tree) Leaf OilLavandula Angustifolia (Lavender) OilEucalyptus Globulus Leaf Oil
Compatibility

Skin types & routine

Routine step cleanser
Time of day Morning & night
Best season All year
Finish matte, natural

Layering

Whip into a thick foam before it touches the face, rinse without rubbing, then follow with a hydrating toner and your acne treatment.

When to expect results

Immediate: a clean, refreshed, matte feel with a herbal scent. Short-term (2-4 weeks): calmer-looking redness around spots for some users. It does not unclog pores in the way exfoliating washes do.

Pairs well with The Acne Barrier medicated lotion or gel creamA leave-on acne treatment such as benzoyl peroxide or adapaleneA light moisturiser
Don't combine with Prescription retinoids on skin that is already dry

A routine built around it

Morning

  1. Ishizawa Lab Acne Barrier Medicated Protect Face Washthis product
  2. Toner
  3. Light moisturiser
  4. Sunscreen

Night

  1. Makeup remover (if needed)
  2. Ishizawa Lab Acne Barrier Medicated Protect Face Washthis product
  3. Acne treatment
  4. Moisturiser
Guidance

How to use it, and who it's for

How to use

Wet your face. Squeeze a small amount into your palm or onto a foaming net, add water and whip it into a thick, dense foam. Spread the foam over the face and let it sit briefly without rubbing, concentrating on oily and breakout-prone areas. Rinse thoroughly with lukewarm water. Follow with toner, acne treatment and moisturiser. Use morning and evening for oily skin, or once daily if your skin feels tight. Remove heavy makeup with a separate remover first.

Is it worth the price?

At about $24.00 for 100 g from Japanese Taste, the wash costs far more than it does in Japanese drugstores, but a small amount foams generously and a tube lasts six to eight weeks. The formula is a competent, milder soap-based cleanser with a calming active, which is reasonable value for oily skin that wants a gentle acne-line wash. It offers less than exfoliating acne cleansers for clogged pores. Ishizawa Lab's long Japanese track record supports its quality.

Who should buy it

People with oily or combination skin and adult breakouts who want a gentle, well-foaming medicated wash with a calming active, especially as part of a routine that includes a leave-on acne treatment.

Who should skip it

People with sensitive, rosacea-prone or eczema-prone skin, or an essential-oil sensitivity, should choose an unscented cleanser. Those looking for exfoliating, pore-clearing action should use a salicylic acid or benzoyl peroxide wash instead.

Ready to try it?Ishizawa Lab Acne Barrier Medicated Protect Face Wash · $24.00 · 100 g
Details

The product, in detail

Texture
A soft, pale green paste that whips into dense, springy foam.
Scent
A herbal blend of tea tree, lavender, rosemary and eucalyptus oils, with no added perfume.
Packaging
A 100 g white tube with a red Acne Barrier label.
How long it lasts
About six to eight weeks with twice-daily use.
Once opened
Use within 12 months · track your toss-by date →
Size
100 g
Made in
Japan

What the first two weeks feel like

Foams well with little product and rinses clean, leaving skin fresh and slightly matte. The herbal scent is noticeable. Reactive skin may tingle from the essential oils.

The story behind it

Why it exists

Ishizawa Lab's Acne Barrier line targets adult acne in Japan, where medicated (quasi-drug) products must declare an approved active. The face wash is the line's first step, paired with a lotion, gel cream and spot essence.

About Ishizawa Lab Established Brand (5–20 years)

Ishizawa Laboratories, founded in Japan in 1996, is a familiar drugstore name behind lines such as Keana Nadeshiko, Toumei Shirohada and the medicated Acne Barrier range. Its products are affordable and widely sold in Japan, though independent clinical data on individual products is limited.

Brand founded 1996

Myth vs. reality

What people get wrong about it

MythA medicated acne wash contains strong acne-fighting chemicals.

RealityIn Japan, many acne quasi-drugs use anti-inflammatory actives such as dipotassium glycyrrhizate, which calm redness rather than exfoliate or kill bacteria.

MythNo added fragrance means it has no scent.

RealityIt contains four essential oils, which give it a herbal scent and can irritate sensitive skin.

FAQ

Questions people ask

What is the active ingredient in the Acne Barrier Medicated Protect Face Wash?

Dipotassium glycyrrhizate, a licorice-derived anti-inflammatory approved for Japanese quasi-drug acne products.

Does the Acne Barrier face wash contain salicylic acid?

No. It relies on dipotassium glycyrrhizate and a soap-and-amino-acid cleansing base rather than exfoliating acids.

Is Ishizawa Lab's Acne Barrier wash fragrance-free?

It has no added perfume, but tea tree, lavender, rosemary and eucalyptus oils give it a noticeable herbal scent.

Can dry skin use the Acne Barrier Protect Face Wash?

It can feel drying because of its soap base; dry or sensitive skin may prefer a gentler, non-soap cleanser.

How should I lather the Acne Barrier face wash?

Whip a small amount into a thick foam with water before applying, then let the foam do the work and rinse without rubbing.

Is the Acne Barrier wash good for body acne?

It is designed for the face, but it can be used on small areas such as the chest if skin tolerates the soap base.

Reviews

What shoppers tend to say

Recurring themes our editors read across retailer reviews — summaries in our words, not quotations, and not a substitute for a patch test.

Common praise

  • Dense, creamy foam
  • Skin feels clean but not tight
  • Refreshing herbal scent

Common complaints

  • Essential-oil scent is strong for some
  • Pricey outside Japan
Related conditions AcneExcess Oiliness
Next stepCheck it against what you already useClashes, spacing and the right order, with everything on your shelf.