Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Serum 80 mL bottle with massage-ball applicator
Strong choice for Dandruff
What makes this different

Most leave-in scalp serums are either fragrance-heavy 'growth' tonics with caffeine and rosemary or medicated dandruff liquids that smell like a pharmacy; this one puts a real antifungal — piroctone olamine — and salicylic acid into a cooling, non-greasy leave-in with a rolling massage-ball applicator, then layers Some By Mi's skincare vocabulary of centella triterpenes and a dozen peptides on top. It behaves like a dandruff-and-oil regulator that happens to be marketed as hair-loss care.

Some By Mi

Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Serum Review

Cooling Scalp Serum Scalp Treatments serum k beauty Paraben free Cruelty free Vegan

Judged as what the label says, an anti-hair-loss serum, this is a dozen trace peptides and a biotin garnish making a promise nothing in the bottle can keep. Judged as what the formula actually is — a cooling leave-in with piroctone olamine and salicylic acid — it is a genuinely useful daily regulator for an oily, itchy, flaky scalp, and the rolling applicator makes it easy to use. Buy it for the flakes, not the follicles, and skip it if your scalp is dry.

Price $20.00 80 mL / 2.7 fl oz
Shopper rating 4.6 ★★★★★ 311 reviews
On the market 2026 Made in South Korea
Buy at Amazon ♥
Verdicts

How well it fits each concern

Only a few months of retail history stand behind this bottle, and the few hundred ratings attached to it are very likely inherited from the tonic it replaced, so first-hand feedback on the reformulated serum is thin. The assessment above therefore relies on the disclosed ingredient order, the well-documented behaviour of piroctone olamine and salicylic acid on the scalp, and the known limits of trace peptides and topical biotin — not on evidence gathered from users of this specific product.

One verdict per concern. Open a row for the reasoning; the receipt has every source.

The scaleRecommendedGoodSupportingEarly evidenceNot for thisAvoidhow it works

Strong choicefor DandruffSalicylic Acid is an approved or monograph active for dandruff; this serum carries it, though the concentration is not declared.ReceiptActive ingredients for the control of dandruff, seborrheic dermatitis, or psoriasis. (opened Aug 11, 2026) · concentration not declared; studied range 1.8–3% · row checked Aug 11, 2026 · rule R3, same reading on 570 products · open the receipt

The case for it

  1. Salicylic Acid is an approved or monograph active for this concern.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries no trigger this concern is sensitive to, with the cautions noted.

Strong evidenceStandard tolerabilityNo reviews read yet

Cautions: known irritants.

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Strong choice” is the verdict on 1,475 of 45,446 concern verdicts across the catalog; rule R3 decided 570 of them. Unchanged since September 25, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All dandruff products →How dandruff is treated →

Promisingfor Excess OilinessSalicylic Acid has trial-level evidence for excess oiliness but no guideline or regulatory standing yet — promising, short of a recommendation; the other actives here are not yet assessed for it.Receipt6 sources on the row · rule R9p, same reading on 4,872 products · open the receipt

The case for it

  1. Salicylic Acid has at least one trial behind it for this concern but no guideline or regulatory standing yet.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries no trigger this concern is sensitive to, with the cautions noted.

Moderate evidenceStandard tolerabilityNo reviews read yet

Cautions: fungal-acne triggers.

What would change this: A declared concentration would move this to a firmer reading of the dose.

Same rule for everyone. “Promising” is the verdict on 4,872 of 45,446 concern verdicts across the catalog; rule R9p decided 4,872 of them. Unchanged since September 25, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All excess oiliness products →

Avoidfor SensitivityThis formula carries drying alcohol — the kind of thing reactive skin flags first.Receiptread from the ingredient list: drying alcohol · rule F1, same reading on 605 products · open the receipt

The case for it

  1. Centella Asiatica Complex has been researched for this concern and the evidence does not support it.
  2. It is plausibly present at a working level, though the concentration is not declared.
  3. The formula carries a known trigger for this concern, which decides the verdict before any efficacy question.

Not from a trial rowCarries a triggerNo reviews read yet

Cautions: known irritants; a declarable fragrance allergen.

What would change this: Removing the trigger named above would let the actives be judged on their own.

Same rule for everyone. “Avoid” is the verdict on 1,912 of 45,446 concern verdicts across the catalog; rule F1 decided 605 of them. Unchanged since September 25, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All sensitivity products →

A verdict is Dermington’s assessment of how well a product’s ingredients fit a concern — never a claim about what the product treats. Evidence dots and collected reviews sit beside it and are never blended in. Rules 0.5.1 · evidence table ev-2026.10-r231 · engine 5.2.0 · how we decide · this product’s receipt

Reader poll · Town SquareQuestion 1 of up to 3

Have you used Cica Peptide Anti Hair Loss Derma Scalp Serum?

One tap counts. A couple of optional follow-ups come next.

No account neededOne answer each, change it any timeCounted only in anonymous totalsHow the Square counts →
Assessment

Pros & cons

What it does well 7

  • Piroctone olamine gives a leave-in real antifungal action against flaking
  • Salicylic acid clears follicle openings on an oily scalp
  • Rolling massage-ball applicator targets partings without drips
  • Dries in a minute and leaves no grease at the roots
  • Menthol and cornmint shut off itch on contact
  • Centella triterpenes, panthenol and allantoin soften the base
  • Affordable for a leave-in with named anti-dandruff actives

Where it falls short 6

  • 'Anti hair loss' is a Korean registration category, not a regrowth result
  • Twelve peptides and biotin sit at trace levels with no hair-density evidence
  • Alcohol denat. in second place dries out a dry or sensitive scalp
  • Menthol stings on scratched, sunburnt or bleached scalps
  • Ball applicator struggles on very dense or curly hair
  • Opaque bottle hides how much serum remains
Review

The full review

Every Korean scalp product seems to carry the same three words, and it is worth knowing where they come from before you spend twenty dollars on them. In Korea, 'hair loss symptom alleviation' is a functional-cosmetic category, a box a product can tick with the Ministry of Food and Drug Safety by including recognised ingredients — biotin, dexpanthenol, certain peptides — at prescribed levels. It is a registration. It is not a trial, not a regrowth result, and not a claim that would survive a regulator in the United States or Europe, where the same words would need evidence nobody in the cosmetics industry has. Some By Mi's Cica Peptide Anti Hair Loss Derma Scalp Serum carries the phrase honestly, in the Korean sense, and the first job of a review is to translate it: this bottle will not grow hair. What it may do is make the scalp you have a better place for hair to live, and on that narrower brief it turns out to be rather good.

The line dates from 2020, when Korean brands collectively decided the scalp was skin and started treating it with skincare vocabulary. Some By Mi, a 2017 brand built on face acids and centella, produced a shampoo, a tonic and a treatment under the Cica Peptide name, and this 2026 serum replaces the tonic as the leave-in: half the volume, a rolling massage-ball applicator, and — the change that matters — piroctone olamine added to the formula. Roll the ball along a parting and it dispenses a thin, clear, water-alcohol liquid that flashes cold within seconds and disappears into the scalp within a minute or two, leaving nothing greasy in the hair.

Read the ingredient list as a scalp product rather than a hair product and it makes immediate sense. Water and alcohol denat. lead, which is the classic base for a leave-in that must dry fast without weighing hair down and is also the first thing a dry scalp will object to. Menthol sits eighth and cornmint oil twelfth, the source of the cold rush the brand describes as lowering scalp temperature. Salicylic acid is tenth, panthenol eleventh, allantoin thirteenth, and then, after a small fraction of argan, olive and sweet almond oils, comes piroctone olamine, the ingredient that changes what this product is. Piroctone olamine is an antifungal with decades of use in dandruff shampoos; it suppresses the Malassezia yeast that drives flaking and itch, and in a leave-in it gets hours of contact with the scalp instead of the thirty seconds a shampoo allows. Paired with salicylic acid to loosen the flakes the yeast produces and to clear the sebum plugging follicle openings, it makes this serum a legitimate low-dose dandruff-and-oil regulator, and that, not the peptides, is the honest reason to buy it.

The peptides, all twelve of them, sit at the bottom of the list between the biotin and the centella triterpenes. Copper tripeptide-1 heads the group and is the only one with any published hair-follicle data, most of it from cell culture and small studies at concentrations a leave-in this price cannot carry. The rest — acetyl hexapeptide-8, a caffeoyl and a galloyl and a nicotinoyl peptide, a run of synthetic 'sh-' peptides — are the vocabulary Korean functional registration rewards, and at trace levels in an alcohol base they are a story printed in small type. Biotin, a few places above them, is the vitamin every hair product includes and that has never been shown to do anything applied to skin; deficiency causes hair loss, and eating biotin fixes deficiency, and neither fact makes a topical trace useful. Nobody should read this as an accusation. Some By Mi is following the rules of its home market, and the formula's real actives are there in plain sight. But a buyer in New York or London reading 'anti hair loss' deserves to know the phrase is doing regulatory work, not biological work.

What the serum does biologically is calm a scalp down, and it does that well if the scalp is the right kind. On an oily, itchy, lightly flaking scalp — the sort that feels grubby by evening and sheds a little snow onto a dark collar — the first application is a relief: the cold shuts off the itch, the roots feel lifted, and the day's oil arrives later and lighter. Over two or three weeks of daily rolling along the crown and hairline the flaking thins and the pink irritation around the parting settles as the piroctone olamine and the centella complex do their slow work. Hair does not become thicker. It does sit better at the roots, which people sometimes read as volume. On a dry or sensitive scalp the story inverts: the alcohol tightens, the menthol stings anywhere the skin is scratched or sunburnt, and by the second week the flaking can look worse rather than better. The brand has put panthenol, allantoin and a little oil in to soften the base, and they help, but they do not change what alcohol denat. in second position does over time.

The applicator deserves credit and a caveat. The rolling ball is a clever piece of design for partings — no dripping, no cold fingers, a small massage as it goes — and it keeps the alcohol off the hair lengths, where it would do no good. On very dense or curly hair it struggles to reach the scalp and dispenses unevenly, and the opaque bottle gives no sense of how much remains. The scent is cornmint and rosemary, sharp for two minutes and then gone with the alcohol; there is no perfume as such, but the essential oils and the limonene they carry are a consideration for anyone with a history of reacting to mint.

At twenty dollars for 80 mL, the serum lasts six to eight weeks used daily on the crown and hairline, or a season used a few times a week between washes. That is fair for a leave-in that carries a real antifungal and a keratolytic in a well-built cooling base, and cheaper than most Western scalp serums, which tend to be either fragrance-heavy caffeine tonics or medicated liquids that smell like a pharmacy. Some By Mi is an emerging brand with no clinical trials of its own products; the serum is a few months old and its ratings are probably pooled with the tonic it replaced, so what you are buying is a sensible formula from a brand that has handled these ingredients since 2020, not proof.

The person it suits has an oily, itchy or lightly flaky scalp, wants a leave-in that dries fast and does not grease the roots, and enjoys a cold rush after a workout or a long day. The person it does not suit has a dry, sensitive or eczema-prone scalp, or is shopping for something to reverse thinning — the first will find the alcohol and menthol unkind, and the second will find nothing in the bottle for them but three well-chosen words.

The science

The evidence in this bottle belongs to the dandruff actives, and it is solid. Piroctone olamine has been compared head-to-head with zinc pyrithione and ketoconazole in shampoo trials for decades. A double-blind, randomised bilateral study by Lodén and Wessman in the International Journal of Cosmetic Science in 2000 tested precisely this serum's pairing — 0.75% piroctone olamine with 2% salicylic acid — against a 1% zinc pyrithione shampoo over four weeks and found both highly effective, with the piroctone-salicylic combination slightly ahead on scaling severity and area. A 2002 study by Piérard-Franchimont and colleagues in the same journal is unexpectedly relevant to the label's other claim: in 150 men with androgenetic alopecia and dandruff, six months of 1% ketoconazole, 1% piroctone olamine or 1% zinc pyrithione shampoo all cleared the dandruff quickly, and the ketoconazole and piroctone groups showed a modest reduction in hair shedding — evidence that controlling scalp inflammation helps retain hair, which is a more defensible reading of 'anti hair loss' than anything the peptides offer. Its concentration here is undisclosed, and the leave-in format is less studied than shampoos, but the longer contact time is mechanistically favourable — most antifungal shampoo data are constrained by a rinse-off of under a minute. Salicylic acid's keratolytic action on scalp scale is recognised in the FDA dandruff monograph at 1.8 to 3% for rinse-off products; the level in this leave-in is certainly lower, consistent with daily low-dose exfoliation rather than a treatment dose.

The hair-loss claim rests on a different and far weaker footing. Copper tripeptide-1 (GHK-Cu) has in-vitro and small in-vivo data suggesting it prolongs follicle anagen and stimulates dermal papilla cells, but the studies used concentrations and delivery systems unlike a trace level in an alcohol tonic, and no controlled trial shows a cosmetic leave-in at this dose changes hair density. The other eleven peptides have essentially no published hair data; they qualify the line for Korea's 'hair loss symptom alleviation' functional-cosmetic registration, which requires listed ingredients at set levels and is not an efficacy finding. Topical biotin has no evidence of follicular uptake or effect; the literature on biotin and hair concerns oral supplementation in deficiency. Rosemary leaf extract is included at a level far below the rosemary oil used in the single small 2015 trial that compared it with 2% minoxidil.

Menthol and cornmint oil act on TRPM8 cold receptors to produce the cooling sensation and a brief interruption of itch signalling — a documented sensory mechanism, not a treatment. The centella triterpenes have anti-inflammatory evidence, mostly from wound-healing and dermatitis models rather than scalp studies. As with every Some By Mi product, no trial of the finished serum exists; the honest summary is that its antifungal and keratolytic components are well supported, its cooling and soothing components are plausible, and its hair-loss components are a regulatory category dressed as a promise.

References 2 ShowHide
  1. The antidandruff efficacy of a shampoo containing piroctone olamine and salicylic acid in comparison to that of a zinc pyrithione shampoo — International Journal of Cosmetic Science (2000)
  2. Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations — International Journal of Cosmetic Science (2002)

The clinical view

Dermatologists who treat scalp complaints tend to draw a firm line between two things patients often conflate: scalp health and hair growth. A leave-in that carries piroctone olamine and salicylic acid addresses the first — seborrhoeic dermatitis, dandruff, the itchy oily scalp that patients scratch until it is sore — and a product that keeps an antifungal on the scalp for hours between washes is a reasonable adjunct to a medicated shampoo, particularly for people who wash infrequently or have textured hair and cannot shampoo daily. The second, hair growth, is where the label overreaches. Korea's functional-cosmetic registration for hair-loss symptom alleviation is well understood by clinicians as a labelling category, and peptides, biotin and rosemary at cosmetic leave-in levels have no evidence base comparable to minoxidil, finasteride or low-level laser therapy; patients noticing genuine thinning would be assessed for androgenetic alopecia, telogen effluvium or nutritional causes rather than directed to a serum. The formulation cautions are the alcohol base and the menthol. Both are poorly tolerated on atopic, psoriatic or otherwise compromised scalp skin, and menthol on excoriated or sunburnt skin is frankly painful, so patients with those conditions would be steered to bland, alcohol-free preparations. For an otherwise healthy, oily, flaky scalp, the serum is a sensible cosmetic-tier option, prescribed expectations included.

Formula

Key ingredients

  1. Piroctone Olamine

    The one ingredient in this serum with a track record against the thing that actually makes scalps flake and itch — it suppresses the Malassezia yeast behind dandruff — and its presence in a leave-in, rather than a rinse-off shampoo, gives it hours of contact time the wash-off version of this line cannot offer.

    Limited for Dandruff
  2. Salicylic Acid

    Tenth on the list, just behind the menthol, the keratolytic loosens the dead-cell and sebum build-up that clogs follicle openings on an oily or flaky scalp; in an alcohol-based leave-in it works as a daily low-dose exfoliant rather than a dandruff treatment dose.

    Regulator-recognised for Dandruff · promising certainty
  3. Menthol + Mentha Arvensis (Cornmint) Leaf Oil

    Eighth on the list and joined by cornmint oil, menthol delivers the instant cold rush the brand markets as 'lowering scalp temperature' — a sensory effect that feels like relief on an itchy scalp and briefly is, but that does nothing for hair and can sting broken or sunburnt skin.

    Not yet assessed
  4. Twelve-Peptide Complex (Copper Tripeptide-1, Acetyl Hexapeptide-8, Caffeoyl Tripeptide-1 and others)

    A dozen signal peptides sit at the bottom of the list, headed by copper tripeptide-1, the only one with any published hair-follicle data; at leave-in trace levels they are the 'anti hair loss' story on the label rather than a dose anyone has shown to thicken hair.

    Not yet assessed
  5. Centella Asiatica Complex (Extract, Asiaticoside, Madecassoside, Asiatic and Madecassic Acid)

    Four isolated centella triterpenes plus the whole extract give the 'Cica' half of the name — anti-inflammatory soothers positioned to calm a red, irritated scalp, and to take the edge off the alcohol and menthol the same formula is built on.

    Not applicable for Sensitivity
  6. Panthenol + Biotin

    Panthenol in eleventh place hydrates the scalp and softens the drying effect of the alcohol base; biotin further down is the vitamin every hair product includes and that, applied topically, has no evidence of reaching a follicle — it is there for the label.

    Not yet assessed
Full ingredient list 43 ingredients ShowHide

Water, Alcohol Denat., C12-13 Alketh-9, Tromethamine, Carbomer, Dipropylene Glycol, 1,2-Hexanediol, Menthol, Hydroxyacetophenone, Salicylic Acid, Panthenol, Mentha Arvensis Leaf Oil, Allantoin, Disodium EDTA, Citric Acid, Argania Spinosa Kernel Oil, Olea Europaea (Olive) Fruit Oil, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Piroctone Olamine, Butylene Glycol, Centella Asiatica Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Hydrolyzed Sweet Almond Protein, Ethylhexylglycerin, Biotin, Acetyl Hexapeptide-8, Copper Tripeptide-1, Caffeoyl Tripeptide-1, Galloyl Pentapeptide-33, Nicotinoyl Tripeptide-47, Nonapeptide-11, sh-Pentapeptide-19, sh-Octapeptide-4, sh-Decapeptide-7, sh-Oligopeptide-9, Tripeptide-31, Tripeptide-55, Asiaticoside, Madecassoside, Asiatic Acid, Madecassic Acid, Limonene

Safety & formulation facts

  • Pregnancy safe
  • Not fragrance free
  • Not alcohol free
  • Not oil free
  • Silicone free
  • Paraben free
  • Sulfate free
  • Cruelty free
  • Vegan
  • Not fungal-acne safe
Pore-clogging (comedogenic) olive fruit oilsweet almond oil
Potential irritants alcohol denat.mentholcornmint oilsalicylic acidlimonene
Common allergens limonenecornmint oilsweet almond oilrosemary extract
Compatibility

Skin types & routine

Routine step serum
Time of day Morning & night
Best season spring & summer
Finish fast-absorbing, lightweight, matte

Layering

Apply to a towel-dried scalp after shampooing, or to a dry scalp between washes, rolling the massage ball along partings at the crown and hairline and massaging in with fingertips — do not rinse. Let it absorb before styling. Skip it on days you use a medicated dandruff shampoo with another antifungal, and keep it off a sunburnt, scratched or freshly bleached scalp, where the alcohol and menthol will sting.

When to expect results

Immediate: a strong cooling rush and quick relief from itch, with the scalp feeling cleaner and less oily for the day. Short term (2-4 weeks): less flaking and redness as the piroctone olamine and salicylic acid take hold, with hair roots feeling less weighed down. Full effect (8-12 weeks): a calmer, better-regulated scalp — the realistic goal; any change in hair density from the peptides is unproven and should not be expected.

Pairs well with gentle sulfate-free shampoothe brand's Cica Peptide shampoolightweight conditioner kept to mid-lengthsscalp sunscreen at partings
Don't combine with prescription minoxidil applied at the same timecoal tar or high-strength salicylic acid scalp treatments the same dayfreshly bleached or chemically treated scalp

A routine built around it

Morning

  1. Shampoo (or skip)
  2. THIS PRODUCT on towel-dried or dry scalp
  3. Styling as usual

Night

  1. Shampoo
  2. Conditioner on lengths only
  3. THIS PRODUCT along partings
Guidance

How to use it, and who it's for

How to use

Shampoo and towel-dry the hair until the scalp is damp rather than wet, or start with a dry scalp between washes. Part the hair, place the massage ball against the scalp and roll it slowly along the parting so the serum dispenses as it goes — the crown and hairline are the usual targets — then repeat on two or three more partings across the areas that itch or flake. Massage in gently with fingertips for half a minute, let it absorb for a minute or two, and style as normal without rinsing. Once a day is plenty; oily scalps can use it morning and evening in hot weather. Avoid a scalp that is sunburnt, scratched or freshly bleached, where the alcohol and menthol will sting, and on days you use a medicated dandruff shampoo, apply the serum at the other end of the day rather than straight after.

Is it worth the price?

Twenty dollars for 80 mL is an accessible price for a leave-in scalp serum with a named antifungal and a keratolytic, and it compares well with Western scalp serums that charge thirty to fifty dollars for caffeine, rosemary and fragrance in a similar alcohol base. Used daily along the crown and hairline the bottle lasts six to eight weeks, closer to a season if reserved for a few applications between washes, which puts it at two to three dollars a week for a real reduction in flaking and oil. The value calculation only holds if you are buying scalp comfort; anyone paying for the 'anti hair loss' promise is paying for a registration category and trace peptides, and would be better served putting the money toward minoxidil or a consultation. Some By Mi's emerging-brand status and lack of product-level trials are reflected in the price, and the serum comes in one size, so there is no larger-format saving.

Who should buy it

People with an oily, itchy or lightly flaking scalp who want a fast-drying leave-in that keeps an antifungal and a mild exfoliant working between washes, who like a cooling sensation, and who have a parting-friendly hair type that the rolling applicator can reach. It is also a sensible companion to the line's shampoo for anyone already using it.

Who should skip it

Dry, sensitive, eczema-prone or psoriatic scalps will find the alcohol base and menthol unkind, and anyone with a sunburnt or scratched scalp should wait for it to heal. Above all, people shopping for something to reverse thinning should look past the label — nothing in this bottle has evidence for regrowth, and a clinician or minoxidil is the better use of the money.

Ready to try it?Some By Mi Cica Peptide Anti Hair Loss Derma Scalp Serum · $20.00 · 80 mL / 2.7 fl oz
Details

The product, in detail

Texture
A thin, clear, water-alcohol gel-liquid with a faint slip from the small oil fraction; it spreads easily along a parting, flashes off in a minute or two and leaves the scalp feeling cool and dry rather than coated.
Scent
Sharp cornmint and menthol with a herbal rosemary edge — no separate perfume, but the essential oils are unmistakable for a few minutes and then fade with the alcohol.
Packaging
An 80 mL bottle topped with a smooth rolling massage ball that dispenses serum as it glides along the scalp, in the line's green-and-white livery; convenient on partings, less so on dense hair, and impossible to see how much is left.
How long it lasts
About 6-8 weeks applying to the crown and hairline once daily; 3 months if used a few times a week between washes.
Once opened
Use within 12 months · track your toss-by date →
Size
80 mL / 2.7 fl oz
Made in
South Korea
Launched
2026
Certifications
Vegan (brand claim) · Korea MFDS functional cosmetic — hair loss symptom alleviation (line registration)

What the first two weeks feel like

The first roll along a parting delivers a hard hit of cold — bracing on an itchy, oily scalp, sharp on any scratched or sunburnt spot — that settles into a pleasant cool within a couple of minutes as the alcohol flashes off. Hair at the roots feels lifted and clean rather than greasy. Over the first fortnight itch and visible flaking ease; anyone with a dry scalp may find the alcohol leaves it tighter by week two.

The story behind it

Why it exists

Some By Mi launched its Cica Peptide scalp line in 2020 as Korean brands began treating the scalp as skin, pairing the centella that anchored its face products with the peptides Korean 'anti hair loss' cosmetics rely on to qualify for functional registration. The original leave-in was a 150 mL tonic; the 2026 serum shrinks the volume, adds piroctone olamine and a rolling applicator, and reached global retailers by summer.

About Some By Mi Emerging Brand (2–5 years)

Some By Mi has sold the Cica Peptide scalp line since 2020, when it extended its skincare actives approach to a shampoo, tonic and treatment; this 2026 serum with a massage-ball applicator is the line's newest leave-in. The brand discloses full ingredient lists and the line carries Korea's 'hair loss symptom alleviation' functional-cosmetic registration, a labelling category rather than a regrowth claim; the brand does not publish its own clinical trials.

Brand founded 2017 · This product since 2026

Myth vs. reality

What people get wrong about it

Myth'Anti hair loss' on the label means the serum regrows hair.

RealityThe phrase reflects Korea's functional-cosmetic category for 'hair loss symptom alleviation', which a product qualifies for by including recognised ingredients at set levels — it is a registration, not a regrowth result. The only topicals with robust trial evidence for regrowth are minoxidil and prescription agents; this serum's peptides sit at trace levels with no comparable data.

MythThe cooling sensation means the scalp is being treated.

RealityThe cold comes from menthol and cornmint oil, which stimulate the skin's cold receptors and briefly interrupt itch signalling. It feels like relief and can be, for a few minutes, but the flake-and-oil work is done by piroctone olamine and salicylic acid, neither of which you can feel.

FAQ

Questions people ask

Does the Some By Mi Cica Peptide Scalp Serum help with hair loss?

It is registered in Korea as a functional cosmetic for 'hair loss symptom alleviation', but that is a labelling category reached by including recognised ingredients, not evidence of regrowth. Its twelve peptides sit at trace levels with no trial data on hair density. What it does well is calm an itchy, flaky, oily scalp — a healthier environment for the hair you have, not a treatment for thinning.

Is the Cica Peptide Scalp Serum good for dandruff?

Yes, this is its real strength. It carries piroctone olamine, an antifungal that suppresses the yeast behind dandruff, plus salicylic acid to loosen flakes, and as a leave-in it keeps both on the scalp for hours rather than seconds. For mild to moderate flaking it works well alone; for heavy dandruff, pair it with a medicated shampoo on alternate days.

Why does the Some By Mi scalp serum feel so cold?

Menthol sits eighth on the ingredient list and cornmint oil follows a few places later; together they trigger the skin's cold receptors, which is what the brand calls 'lowering scalp temperature'. The rush fades in a couple of minutes as the alcohol flashes off. It is a sensory effect — pleasant on an itchy scalp, too sharp on a scratched or sunburnt one.

Can I use the scalp serum on a dry scalp?

Cautiously. Alcohol denat. is the second ingredient, and daily use on an already dry scalp can leave it tighter and flakier over a couple of weeks, even with the panthenol and small oil fraction offsetting it. Oily, itchy or flaky scalps suit it best; dry scalps do better with an oil- or water-based soothing serum.

Do I rinse the Cica Peptide Scalp Serum out?

No — it is a leave-in. Roll the massage ball along partings on a towel-dried or dry scalp, massage in with fingertips and let it absorb for a minute or two before styling. Rinsing would remove the piroctone olamine and salicylic acid that need contact time to work.

Can the scalp serum be used with minoxidil?

Yes, but not in the same application. Apply minoxidil first to a dry scalp and let it absorb fully, then use the serum at a different time of day, since the alcohol base of both products applied together raises the irritation risk. The serum will not add to minoxidil's regrowth effect; it addresses scalp comfort, not follicle stimulation.

Reviews

What shoppers tend to say

Recurring themes our editors read across retailer reviews — summaries in our words, not quotations, and not a substitute for a patch test.

Common praise

  • Cooling sensation calms an itchy scalp within seconds
  • Massage-ball applicator makes partings easy to target
  • Flaking and oiliness settle within a few weeks
  • Absorbs without leaving hair greasy or crunchy

Common complaints

  • Menthol tingle is too intense for sensitive scalps
  • Alcohol base can feel drying on the scalp over time
  • No visible effect on hair thickness
  • Ball applicator dispenses unevenly on thick hair
Notable endorsementsNewest leave-in of Some By Mi's Cica Peptide scalp line, sold since 2020Line registered in Korea as a functional cosmetic for 'hair loss symptom alleviation'
Next stepCheck it against what you already useClashes, spacing and the right order, with everything on your shelf.