The Ordinary Multi-Peptide Lash and Brow Serum slim white 5 ml tube with brush cap
What makes this different

It is the lash serum built by leaving out the ingredient that makes lash serums work dramatically, the prostaglandin analogue, and putting in its place the cosmetic peptides the category has used since, myristoyl pentapeptide-17 fourth on the list with three hair-cycle peptides, caffeine, panthenol and conditioning proteins, all fragrance-free and under fifteen dollars; the trade is a glossier, softer lash with a modest chance of length rather than a guaranteed dramatic one with a lid-darkening risk.

The Ordinary

The Ordinary Multi-Peptide Lash and Brow Serum Review

Prostaglandin-Free Lash Serum Spot Treatments liquid clinical Paraben free Fungal-acne safe Cruelty free Vegan

The lash serum that leaves out the ingredient that makes lash serums work dramatically, and is safer and gentler for it: myristoyl pentapeptide-17 at its supplier's dose, three hair-cycle peptides, caffeine, panthenol and conditioning proteins, fragrance-free, under fifteen dollars. Reliably glossier, softer lashes within weeks; a modest, unreplicated chance of length over a lash cycle; none of the prostaglandin risks and none of the prostaglandin results.

Price $14.90 5 ml / 0.17 fl oz
On the market 2020 Made in Canada
Buy at Amazon ♥
Verdicts

How well it fits each concern

No concern verdicts yet.

The scaleRecommendedGoodSupportingEarly evidenceNot for thisAvoidhow it works

A verdict is Dermington’s assessment of how well a product’s ingredients fit a concern — never a claim about what the product treats. Evidence dots and collected reviews sit beside it and are never blended in. Rules 0.5.1 · evidence table ev-2026.10-r231 · engine 5.2.0 · how we decide · this product’s receipt

Reader poll · Town SquareQuestion 1 of up to 3

Have you used Multi-Peptide Lash and Brow Serum?

One tap counts. A couple of optional follow-ups come next.

No account neededOne answer each, change it any timeCounted only in anonymous totalsHow the Square counts →
Assessment

Pros & cons

What it does well 6

  • No prostaglandin analogue, so none of the lid-darkening, iris or orbital-fat risks
  • Myristoyl pentapeptide-17 fourth on the list, at its supplier's recommended dose
  • Three further hair-cycle peptides, caffeine and panthenol for follicle and shaft support
  • Glycoproteins and amino acids leave lashes glossier and more flexible within weeks
  • Fragrance-free, alcohol-free, oil-free, vegan and safe around extensions
  • Under fifteen dollars for a full lash cycle of nightly use

Where it falls short 6

  • Peptides rest on supplier studies with no independent replication
  • No dramatic lengthening; many users see gloss without growth
  • Tiny 5 ml tube lasts two to three months at a stroke a night
  • Stings if it migrates into the eye, so lower lashes are off limits
  • Sodium metabisulfite and benzoic acid are notes for sensitive users
  • Brand publishes no trial of the serum
Review

The full review

The most important thing on this ingredient list is what is not on it. The lash serums that made the category famous in the 2010s worked because they contained prostaglandin analogues, cousins of the glaucoma drug bimatoprost, which act on the follicle's growth cycle with drug-level potency and produced dramatic lengthening along with darkened lids, permanently browned irises in some users, and a hollowing of the eye socket as orbital fat thinned. The Ordinary's serum, launched in 2020, contains none of that. Its list is water, glycols, four cosmetic peptides, caffeine, panthenol, a few extracts borrowed from the brand's hair density serum, conditioning proteins and preservatives, and everything that follows from that choice, the safety and the modesty alike, is the review.

The peptides are the cosmetic industry's replacement for the prostaglandins, and they come with the industry's kind of evidence. Myristoyl pentapeptide-17 is fourth on the list, straight after the humectants, which puts it at or near its supplier's recommended dose; the supplier sells it as a stimulator of keratin genes in the lash follicle on the strength of a study reporting longer-looking lashes after a few weeks, and nobody has replicated it. Biotinoyl tripeptide-1, oligopeptide-2 and acetyl tetrapeptide-3 follow at fifth to seventh, hair-cycle peptides from the scalp-serum world with supplier data of the same kind. Caffeine at eighth has laboratory evidence in cultured hair follicles for countering testosterone's suppression of growth, which is real if not lash-specific, and panthenol at ninth conditions the shaft. Larch, red clover and green tea extracts, the botanical halves of the Redensyl and Capixyl complexes, sit further down. One small independent trial exists for the category, a 2024 open clinical study of a peptide-and-glycosaminoglycan lash enhancer reporting improved lash appearance over weeks, which is the closest thing to outside support and is not a study of this product. The honest reading is a formula assembled from the best-marketed cosmetic lash ingredients at sensible levels, with a rationale and no proof.

What the serum reliably does is not what the peptides are for. Glycoproteins, arginine, glycine and panthenol coat and soften the lash shaft, and within a week or two lashes are glossier, more flexible and less brittle, which is the effect most users notice first and read as fuller. That is a conditioning result, not a growth one, and it is genuine. Length and density, if they change, take a lash cycle of six to twelve weeks to show, and six years of divided reviews say what the evidence predicts: a good share of users report longer or thicker lashes at two or three months, a good share report only the gloss, and almost nobody reports the dramatic change a prostaglandin serum gives. Brows, which cycle slower, follow the same pattern more slowly. Anyone who has over-plucked brows for years should also know that follicles closed by long-term traction do not reopen for a peptide, and that the serum's realistic brow contribution is darker-looking, better-conditioned hairs rather than new ones.

The safety side is where leaving out the prostaglandin pays. There is no lid darkening, no iris risk, no fat loss, no redness for most users, and the serum is fragrance-free, alcohol-free, oil-free and vegan; the only ingredients of note are sodium metabisulfite, for the sulfite-sensitive, and benzoic acid in the preservative system, and the only reliable complaint is a brief sting when the gel gets into the eye, which is why the instructions say one stroke along the base of the upper lashes and nothing on the lower ones. It is water-based, so it does not dissolve extension adhesive, and it goes on before eye cream rather than over it.

Under fifteen dollars for 5 ml sounds small until the dose is counted: a single stroke a night along the upper lash line and through the brows makes the tube last two to three months, a full lash cycle, which is exactly the length of trial the peptides need to be judged. Prostaglandin-free peptide lash serums from prestige brands cost fifty to a hundred dollars for the same or smaller volumes with the same supplier evidence, and the prescription drug costs more still and carries its risks. The Ordinary's version has been in the range since 2020 with a review history far larger than any single count captured this session, and the brand publishes no trial of it, which for a cosmetic lash serum is the industry norm rather than a mark against it.

For anyone who wants their lashes to look healthier, softer and glossier without risking their eyelids, and who is content with a modest, uncertain chance of length on top, this is the sensible, cheap, well-made choice and the one a cautious ophthalmologist would prefer. For anyone who wants the transformation the notorious serums delivered, the absence on this label is exactly the point, and it cuts both ways.

The science

The evidence behind peptide lash serums is thin and this one is representative of it. The category's mechanism claims trace to the prostaglandin analogues, which lengthen the anagen phase of the lash follicle with drug-level potency and have randomised trial support, bimatoprost being approved for hypotrichosis of the eyelashes, along with documented adverse effects on lid pigmentation, iris colour and periorbital fat; The Ordinary's serum contains no prostaglandin analogue and therefore neither the efficacy nor the risks of that class. Its peptides carry supplier data. Myristoyl pentapeptide-17 is marketed on a supplier study reporting increased lash length after a few weeks of use with a proposed mechanism of keratin gene stimulation; biotinoyl tripeptide-1, oligopeptide-2 and acetyl tetrapeptide-3 have supplier studies on scalp hair for follicle anchoring, IGF-1 signalling and anagen support; none has been independently replicated and none has been tested on lashes in a controlled setting. The independent literature offers one relevant study, a 2024 open clinical trial in the Journal of Cosmetic Dermatology of a lash enhancer combining peptides and glycosaminoglycans that reported improved lash appearance over the study period, uncontrolled and not of this formula. Caffeine has independent laboratory evidence in cultured human scalp follicles for countering testosterone-mediated growth suppression and prolonging anagen, which supplies a mechanism without a lash trial. The serum's reliable effect has a simpler basis: glycoproteins, amino acids and panthenol condition the keratin of the lash shaft, increasing flexibility and gloss and reducing breakage, which improves lash appearance within weeks independent of any change in growth. The base is bland, and sodium metabisulfite is the one ingredient with a documented sensitisation record. No trial of the serum exists, and the assessment rests on the category's literature and six years of user feedback.

References 2 ShowHide
  1. Open clinical trial evaluating the efficacy of a novel eyelash growth enhancer with peptides and glycosaminoglycans — Journal of Cosmetic Dermatology (2024)
  2. Effect of caffeine and testosterone on the proliferation of human hair follicles in vitro — International Journal of Dermatology (2007)

The clinical view

Lash serums divide neatly in clinical advice into the prostaglandin class, which works and carries real ocular and periorbital side effects, and the peptide class, which is safe and largely unproven, and this serum belongs firmly to the second; dermatologists and ophthalmologists who discourage patients from cosmetic prostaglandin serums because of lid darkening, iris change and orbital fat loss generally regard a peptide formula like this as harmless and possibly mildly helpful for lash condition. The cautions raised are minor: keep it out of the eye, where it stings, apply it after contact lenses are out, patch-test for eyelid eczema, and note the sulfite for sensitised patients. Patients with genuine lash loss from alopecia areata, thyroid disease, chemotherapy or trichotillomania would be told that a cosmetic serum does not address the cause and that prescription bimatoprost is the treatment with evidence, while accepting its risks. For a person who wants glossier, less brittle lashes with no hazard, it is a reasonable choice.

Formula

Key ingredients

  1. Myristoyl Pentapeptide-17

    Fourth on the list, straight after the humectants, the peptide the cosmetic lash category was built on: a fatty-acid-linked pentapeptide sold by its supplier as a keratin-gene stimulator for the lash follicle, with a supplier study reporting longer-looking lashes after a few weeks and no independent replication. Its position here is high enough to be at the supplier's recommended dose, which is the most any cosmetic lash serum offers.

    Not yet assessed
  2. Biotinoyl Tripeptide-1, Oligopeptide-2 and Acetyl Tetrapeptide-3

    Fifth to seventh, three further hair-cycle peptides borrowed from scalp serums, the biotin-linked tripeptide of Procapil, an IGF-1-mimicking oligopeptide and the anchoring tetrapeptide of Capixyl, each with supplier data for follicle support; on lashes and brows, which cycle faster and shorter than scalp hair, they are a plausible, unproven supporting set.

    Not yet assessed
  3. Caffeine and Panthenol

    Eighth and ninth, the follicle stimulant with laboratory evidence in cultured hair follicles and the provitamin that conditions the hair shaft and skin; together they are the serum's most credible pairing for stronger-feeling, less brittle lashes, if not for longer ones.

    Not yet assessed
  4. Larch Wood Extract, Red Clover Flower Extract and Green Tea

    Positions thirteen to fifteen, the botanical halves of the Redensyl and Capixyl complexes plus green tea catechins, the same supplier-studied extracts as the brand's scalp serum at lower positions; here they are supporting notes in a formula where the peptides do the claiming.

    Not yet assessed
  5. Glycoproteins, Arginine and Glycine

    Conditioning proteins and amino acids that coat and soften the lash shaft, which is where a lash serum's immediate, visible effect, glossier and more flexible lashes, actually comes from; they do not change growth but they change how the lashes look and feel within days.

    Not yet assessed
Full ingredient list 31 ingredients ShowHide

Aqua (Water), Glycerin, Butylene Glycol, Myristoyl Pentapeptide-17, Biotinoyl Tripeptide-1, Oligopeptide-2, Acetyl Tetrapeptide-3, Caffeine, Panthenol, Arginine, Glycine, Glycoproteins, Larix Europaea Wood Extract, Trifolium Pratense Flower Extract, Camellia Sinensis Leaf Extract, Dextran, Maltodextrin, Zinc Chloride, Hydroxyethylcellulose, Xanthan Gum, Trisodium Ethylenediamine Disuccinate, Polysorbate 20, Sodium Metabisulfite, Caprylyl Glycol, 1,2-Hexanediol, Sodium Benzoate, Benzoic Acid, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin

Safety & formulation facts

  • Pregnancy safe
  • Fragrance free
  • Alcohol free
  • Oil free
  • Silicone free
  • Paraben free
  • Sulfate free
  • Cruelty free
  • Vegan
  • Fungal-acne safe
Potential irritants Sodium MetabisulfiteBenzoic Acid
Common allergens Sodium Metabisulfite
Compatibility

Skin types & routine

Routine step treatment
Time of day Night
Best season All year
Finish invisible

Layering

Once a day, at night, on a clean, dry lash line and brows before any eye cream: a single stroke of the brush along the base of the upper lashes, like a liquid liner, and a stroke through each brow, left to dry for a minute before anything else goes near the eyes. It sits under eye cream and under mascara the next morning, and it should not be applied over makeup, over an eye cream or onto the lower lashes, where it migrates into the eye. Contact-lens wearers should apply it after lenses are out.

When to expect results

Glossier, softer, more flexible lashes within a week or two from the conditioning proteins and panthenol, which reads as fuller and is the effect most users notice first; any change in length or density, if it comes, takes six to twelve weeks, the length of a lash cycle, and the supplier studies behind the peptides report modest gains on that timescale without independent confirmation. It does not produce the dramatic lengthening of prostaglandin serums, and it does not darken the lid, change eye colour or thicken the skin, because it contains nothing that can.

Pairs well with eye-creammascaragentle-eye-makeup-remover

A routine built around it

Morning

  1. Cleanser
  2. Eye cream
  3. Mascara

Night

  1. Eye makeup remover and cleanser
  2. THIS PRODUCT along the upper lash line and brows
  3. Eye cream after a minute
Guidance

How to use it, and who it's for

How to use

At night, remove eye makeup and cleanse, then dry the lash line and brows completely. Unscrew the cap, wipe excess gel from the brush against the tube's rim, and draw a single stroke along the base of the upper lashes from inner to outer corner, as if applying liquid liner, then a stroke through each brow along the direction of growth. Let it dry for about a minute before applying eye cream or anything else near the eyes. Do not apply to the lower lashes, over makeup or eye cream, or into the eye, and apply after contact lenses have been removed. Use nightly for at least three months before judging length, expect glossier lashes within a couple of weeks, and stop if the lids itch or redden.

Is it worth the price?

Fourteen dollars and ninety cents for 5 ml is the lowest price in its category by a wide margin, and a single stroke a night along the upper lash line and brows makes the tube last two to three months, a full lash cycle, so the cost of a proper trial is under fifteen dollars; prostaglandin-free peptide serums from prestige brands cost fifty to a hundred dollars with the same supplier evidence, and the prostaglandin serums cost as much again with their risks attached. The money buys sensibly dosed cosmetic peptides, caffeine, panthenol, conditioning proteins, a precise brush and a formula free of anything that can harm the eye; it buys no guarantee of length. Excellent value for what the class can do, which is modest.

Who should buy it

People who want softer, glossier, less brittle lashes and brows with a modest chance of extra length, without the lid darkening, iris and orbital risks of prostaglandin serums, at a price that makes a three-month trial trivial. It suits sensitive eyes, extension and lash-lift wearers who need an oil-free formula, and anyone who has been warned off the prostaglandin class.

Who should skip it

Anyone expecting the dramatic lengthening of a prostaglandin serum, which this deliberately does not contain. People with genuine lash loss from a medical cause, who need a diagnosis and, where appropriate, prescription bimatoprost rather than a cosmetic. And sulfite-sensitive or very reactive eyelids that have not patch-tested the gel.

Ready to try it?The Ordinary Multi-Peptide Lash and Brow Serum · $14.90 · 5 ml / 0.17 fl oz
Details

The product, in detail

Texture
A clear, thin, water-light gel applied with a fine brush that lays a barely visible line along the lash base, dries within a minute to nothing, and leaves lashes feeling slightly softer and more flexible rather than coated.
Scent
None; unfragranced, with no detectable scent from the gel.
Packaging
A slim white 5 ml tube with a fine liner-style brush under a screw cap, printed in The Ordinary's plain black type with Multi-Peptide Lash and Brow Serum and a short description; the brush applies a precise line along the lash base and through the brows, and the tube is small enough to travel.
How long it lasts
About two to three months at a nightly stroke along the upper lash line and brows.
Once opened
Use within 12 months · track your toss-by date →
Size
5 ml / 0.17 fl oz
Made in
Canada
Launched
2020
Certifications
Vegan · Cruelty-free

What the first two weeks feel like

The first application is a single stroke along the upper lash line and through each brow, which dries in a minute and is forgotten; within a week or two lashes feel softer and look glossier, which is the conditioning proteins and panthenol and which most users read as fuller. Length, if it changes, takes a lash cycle of six to twelve weeks to show, and a fair share of users report no change at all, with no redness, darkening or irritation along the way unless the gel gets into the eye, where it stings briefly.

The story behind it

Why it exists

The prescription lash drug bimatoprost and its cosmetic prostaglandin cousins made dramatic lash growth possible in the 2010s and brought with them lid darkening, iris colour change and orbital fat loss, which sent a share of the market looking for something gentler; The Ordinary's 2020 serum was the brand's answer, a peptide formula borrowing the complexes from its hair density serum and applied with a liner brush, and it became one of the brand's most-searched products on the strength of its price and the safety of its ingredient list.

About The Ordinary Established Brand (5–20 years)

The Ordinary, DECIEM's Toronto flagship founded in 2016 and owned by Estée Lauder since 2021, prices declared actives at drugstore levels and names the complexes it licenses; this lash and brow serum, in the range since 2020, is the brand's deliberately prostaglandin-free answer to the category, built on cosmetic peptides with supplier-funded studies, and the brand publishes no trial of the serum itself.

Brand founded 2016 · This product since 2020

Myth vs. reality

What people get wrong about it

MythA peptide lash serum grows lashes the way a prostaglandin serum does.

RealityProstaglandin analogues act on the follicle's growth cycle with drug-level potency and a matching side-effect list; myristoyl pentapeptide-17 and its companions are cosmetic peptides with supplier studies reporting modest gains and no independent replication. This serum's reliable effect is glossier, more flexible lashes from its conditioning proteins, and length is a possibility rather than a promise.

MythLash serums are risky for the eyes, so this one must be too.

RealityThe risks that made lash serums notorious, lid darkening, iris colour change and orbital fat loss, belong to prostaglandin analogues, and this serum contains none; its ingredient list is water, glycols, peptides, caffeine, panthenol and preservatives, and the only hazard is a brief sting if it gets into the eye. Sodium metabisulfite is a note for sulfite-sensitive users.

FAQ

Questions people ask

Does The Ordinary Multi-Peptide Lash and Brow Serum contain prostaglandins?

No; it is built on cosmetic peptides, myristoyl pentapeptide-17, biotinoyl tripeptide-1, oligopeptide-2 and acetyl tetrapeptide-3, with caffeine and panthenol, and contains no prostaglandin analogue, so it carries none of the lid-darkening, iris-colour or orbital-fat risks of that class. It also produces none of their dramatic lengthening.

Does The Ordinary lash serum actually make lashes longer?

Reliably it makes them softer, glossier and more flexible within a couple of weeks through its conditioning proteins and panthenol, which reads as fuller; any change in length or density takes a full lash cycle of six to twelve weeks and rests on supplier studies of the peptides that have not been independently replicated. Many users see the gloss and not the length.

How is The Ordinary lash and brow serum applied?

Once a day at night on clean, dry skin, draw a single stroke with the brush along the base of the upper lashes like a liquid liner and a stroke through each brow, then let it dry for a minute before eye cream; keep it off the lower lashes and out of the eye, where it stings, and apply it after contact lenses are out.

Is The Ordinary lash serum safe for sensitive eyes?

Generally yes; it is fragrance-free, alcohol-free, oil-free and free of prostaglandins, and the peptides and caffeine are mild. Sodium metabisulfite and benzoic acid are notes for sulfite-sensitive or very reactive users, and anyone with eyelid eczema should patch-test on the arm first.

How long does a tube of The Ordinary lash and brow serum last?

About two to three months at a nightly stroke along the upper lash line and through the brows, which is enough to see a full lash cycle through; at under fifteen dollars a tube that is a cheap trial, and results should be judged at three months rather than three weeks.

Can The Ordinary lash serum be used with eyelash extensions or a lash lift?

It is water-based and oil-free, so it does not dissolve extension adhesive the way oils do, and it can be applied along the natural lash base after a lift; apply it to clean, dry lashes and let it dry before anything else, and check with the technician if extensions are fresh.

Reviews

What shoppers tend to say

Recurring themes our editors read across retailer reviews — summaries in our words, not quotations, and not a substitute for a patch test.

Common praise

  • Softer, glossier, healthier-looking lashes within weeks
  • No irritation, redness or lid darkening
  • Fine brush is easy to apply along the lash line
  • Cheap enough to use nightly for months

Common complaints

  • No real lengthening for many users
  • Tiny 5 ml tube runs out in two to three months
  • Slower and subtler than prostaglandin serums
  • Stings if it gets into the eye
Next stepCheck it against what you already useClashes, spacing and the right order, with everything on your shelf.