Hada Labo Gokujyun Adlay Trouble Care Skin Conditioning Lotion mint green bottle
Not yet assessed for Acne
What makes this different

It is the outlier in the Gokujyun family: instead of hyaluronic acid and almost nothing else, it is a Japanese quasi-drug with two registered anti-inflammatory actives, dipotassium glycyrrhizate and epsilon-aminocaproic acid, carried in ethanol with menthol and camphor for a cooling, pore-tightening finish and adlay, fish mint and chamomile as the kampo garnish. A fourteen-dollar medicated toner for oily, breakout-prone Japanese summers, sold abroad under the Trouble Care name.

Hada Labo

Hada Labo Gokujyun Adlay Trouble Care Skin Conditioning Lotion Review

Medicated Cooling Toner Toners liquid j beauty Paraben free Not cruelty free

The Gokujyun that is nothing like the others: a fourteen-dollar Japanese medicated toner with two registered anti-inflammatory actives in an alcohol, menthol and camphor base, cooling and tightening on a hot, oily face and stinging on anything else. For breakout-prone summer skin it is a cheap, effective preventive; for dry, sensitive or barrier-compromised skin it is the wrong bottle on the right shelf.

Price $13.85 170 ml / 5.7 fl oz · more sizes
Shopper rating 4.3 ★★★★★ 800 reviews
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Verdicts

How well it fits each concern

One verdict per concern. Open a row for the reasoning; the receipt has every source.

The scaleRecommendedGoodSupportingEarly evidenceNot for thisAvoidhow it works

Supporting rolefor DehydrationNothing here targets dehydration directly; humectant hydration is the recognised companion to treating it, and this liquid does that without known triggers.ReceiptDipotassium Glycyrrhizate: no evidence row for this concern yet · rule R8, same reading on 3,793 products · open the receipt

The case for it

  1. Dipotassium Glycyrrhizate has no evidence row yet for this concern — it is in the research queue.
  2. The formula carries no trigger this concern is sensitive to, with the cautions noted.

Not from a trial rowStandard tolerabilityNo reviews read yet

Cautions: drying alcohol.

What would change this: A researched evidence row for the lead active would replace this with a verdict.

Same rule for everyone. “Supporting role” is the verdict on 7,796 of 45,446 concern verdicts across the catalog; rule R8 decided 3,793 of them. Unchanged since September 25, 2026, engine 5.2.0.

Brand or formulator? Disclose a concentration or correct a fact →

The full receipt: rule, row, sources, dates →All dehydration products →

Also listed for Acne, Excess Oiliness and Rough Texture — the actives here (Licorice Root Extract, aminocaproic acid, Coix Seed, Chamomile Extract) are in our research queue for those concerns; there is no verdict until their evidence rows are written. That is a gap in our table, not a mark against the product.

Falls shortJudged as a toner, it comes up short on: adds something real. Not measured from the label: restores skin pH, plays well with what follows.

A verdict is Dermington’s assessment of how well a product’s ingredients fit a concern — never a claim about what the product treats. Evidence dots and collected reviews sit beside it and are never blended in. Rules 0.5.1 · evidence table ev-2026.10-r231 · engine 5.2.0 · how we decide · this product’s receipt

Reader poll · Town SquareQuestion 1 of up to 3

Have you used Gokujyun Adlay Trouble Care Skin Conditioning Lotion?

One tap counts. A couple of optional follow-ups come next.

No account neededOne answer each, change it any timeCounted only in anonymous totalsHow the Square counts →
Assessment

Pros & cons

What it does well 7

  • Two registered quasi-drug anti-inflammatory actives, glycyrrhizate and aminocaproic acid
  • Cooling, quick-drying finish that oily skin in summer genuinely enjoys
  • Reduces the frequency of small breakouts over a few weeks of daily use
  • No fragrance, colourant, mineral oil or parabens
  • Adlay, fish mint and chamomile leave skin soft once the alcohol flashes off
  • Thirteen dollars and eighty-five cents with a refill pouch available
  • More than a decade of pharmacy sales and a stable formula

Where it falls short 6

  • Two grades of alcohol plus menthol and camphor sting on dry or irritated skin
  • Not hydrating enough to stand alone outside summer
  • Preventive only, with nothing to clear existing spots
  • Medicinal menthol-and-camphor smell despite no added fragrance
  • The Gokujyun name misleads sensitive-skin buyers expecting the hyaluronic lotion
  • Cannot be paired with a retinoid or acid on the same night
Review

The full review

The first thing this lotion does is go cold. Splash it on after a hot shower and there is a rush of menthol, a faint whiff of camphor and ethanol, and a tight, clean, almost squeaky feel as the alcohol flashes off, all in the space of a minute. It is bracing, and on an oily face in August it is a small pleasure. It is also the opposite of what anyone who knows Hada Labo expects, because the brand built its name on a hyaluronic lotion so bland and alcohol-free that the most reactive skin in Japan can bathe in it. The Gokujyun Adlay Trouble Care Skin Conditioning Lotion is Rohto's answer to the customer that lotion was too rich for, and it is a different product wearing the same name.

The declaration explains it, read the Japanese way with actives first. Dipotassium glycyrrhizate, the anti-inflammatory salt of licorice, and epsilon-aminocaproic acid, an antifibrinolytic amino acid that Japanese pharmacies use to calm irritated skin; those two are the quasi-drug actives, approved by the health ministry for preventing acne and rough skin. Then the supporting cast: adlay seed extract, the Job's tears that Japanese grandmothers have recommended for bumpy skin for generations and that gives the product its name; fish mint and chamomile for calming; a single hyaluronate and a trace of squalane so it is not entirely stripping; camphor and menthol for the cold; butylene glycol, a triglyceride, an emulsifier and a solubiliser; a chelator; and two grades of ethanol to carry all of it. No fragrance, no colourant, no mineral oil, no parabens. Fifteen ingredients, and only two of them are Hada Labo's usual idea of a good time.

What it does for its intended skin is modest and real. Glycyrrhizate is one of the better-documented cosmetic anti-inflammatories, and epsilon-aminocaproic acid, a close relative of tranexamic acid, is a standard quasi-drug pairing with it in Japan; used twice daily on oily, breakout-prone skin, the pair takes the edge off redness and, over two to four weeks, reduces the small, frequent spots that come with an oily T-zone in humid weather. The alcohol keeps the surface clean and dry, the menthol makes it feel like the pores are closing, and the adlay and botanicals leave the skin soft rather than parched once the flash-off is done. It does not clear a breakout that already exists; it is a preventive, and the honest place for it is as the first step on a summer morning for skin that would otherwise shine by noon.

What it does for the wrong skin is the reason to read this review before buying. Alcohol, menthol and camphor together are a triad that dermatology associates with sting, dryness and, on a barrier that is already compromised, worsening irritation; the cooling is a nerve sensation, not an anti-inflammatory effect, and camphor in particular is an ingredient clinicians steer eczema and rosacea patients away from. On dry skin this lotion tightens rather than hydrates and needs a milk or cream on top to be tolerable; on freshly exfoliated, retinoid-treated or sunburnt skin it stings outright. The adlay on the front and the Gokujyun name on the label give an impression of gentleness that the base does not honour, and that mismatch accounts for most of the unhappy reviews.

The folk hero deserves a fair word. Adlay, hatomugi, coix seed, Job's tears: the same grain under four names, boiled into tea and pressed into lotions across Japan, Korea and China for rough, bumpy skin. Its polysaccharides are humectant and its tradition is deep; its evidence for anything beyond softening is thin, and Rohto, to its credit, hangs the acne claim on the two registered actives rather than on the grain. The fish mint has mouse-model data for dermatitis and chamomile a long anti-irritant record, and both sit at extract level. It is the actives and the alcohol that define the product.

More than a decade in Japanese pharmacies, Japanese reviews going back to at least 2016 and a healthy, split verdict online say the same thing: oily, breakout-prone users, often teenagers and their parents buying for them, are pleased; dry and sensitive users who bought it for the brand name are not. It comes with a refill pouch, it lasts about two months at a generous splash, and at thirteen dollars and eighty-five cents it is cheap enough to use with abandon, which is how a cooling toner is meant to be used.

So the recommendation is narrow and clear. Oily and combination skin, especially in hot weather, that wants a medicated, cooling, drying first step with two real anti-inflammatory actives and no fragrance, at a price that invites generosity: this is a good buy and a Japanese pharmacy classic. Everyone else in the Hada Labo customer base, which is to say most of it, should reach past this bottle for the hyaluronic lotion beside it and treat breakouts with something built for the job.

The science

The lotion's claim rests on two registered actives whose evidence is respectable and whose job is narrow. Dipotassium glycyrrhizate is the water-soluble salt of glycyrrhizin from licorice root, and licorice derivatives are among the best-supported botanical anti-inflammatories in dermatology; a 2010 evidence-based review of botanicals in the American Journal of Clinical Dermatology placed licorice among the plant extracts with credible anti-inflammatory and skin-calming data, and glycyrrhizate is a staple quasi-drug active in Japan for exactly the acne-and-rough-skin claim this product carries. Epsilon-aminocaproic acid is an antifibrinolytic amino acid, a close relative of tranexamic acid, that Japanese formulators use as an anti-inflammatory for irritated skin; its cosmetic literature is thin outside Japan, and its role here is best understood as a regulator-recognised partner to the glycyrrhizate rather than an independently evidenced active.

The botanicals are traditional with pockets of laboratory support. Coix seed, the adlay of the name, has a long East Asian record for rough skin and humectant polysaccharides but little clinical data in topical use. Houttuynia cordata has mouse-model studies in which its polysaccharides and fermentation products reduced atopic-dermatitis-type inflammation and barrier damage, reviewed comprehensively in Phytomedicine in 2024, without human trials of a cosmetic extract. Chamomile has a long anti-irritant record and is also a recognised, if uncommon, contact allergen.

The base is the clinically relevant part for anyone outside the target skin type. Ethanol at the levels a thin Japanese toner uses evaporates quickly and degreases the surface, which oily skin experiences as freshness and dry or compromised skin experiences as tightening and, with repeated use, barrier disruption. Menthol and camphor act on cold-sensing nerve receptors to produce the cooling sensation; the effect is sensory, not anti-inflammatory, and both are counter-irritants that can sting and worsen dermatitis on a damaged barrier, which is why they are discouraged on rosacea, eczema and post-procedure skin. The single sodium hyaluronate and trace of squalane soften the finish but do not offset the alcohol's drying on skin that lacks oil to spare. The formula is, in short, well matched to oily skin and mismatched to the sensitive skin the brand is known for.

References 2 ShowHide
  1. Botanicals in dermatology: an evidence-based review — American Journal of Clinical Dermatology (2010)
  2. Houttuynia Cordata Thunb.: A comprehensive review of traditional applications, phytochemistry, pharmacology and safety — Phytomedicine (2024)

The clinical view

Medicated Japanese toners of this type are familiar in clinical discussion as reasonable adjuncts for oily, mildly acne-prone skin and as frequent culprits when a patient with sensitive skin reports stinging from a product they chose for its gentle-sounding brand. The two registered anti-inflammatory actives are sound, and glycyrrhizate in particular is well regarded; the reservation is entirely about the vehicle. Alcohol, menthol and camphor together are the ingredients most consistently advised against in rosacea, eczema, perioral dermatitis and any barrier-compromised state, and their cooling sensation is often mistaken by patients for a therapeutic effect. For acne itself the lotion is a preventive complement, not a treatment; the evidence-based over-the-counter tools remain benzoyl peroxide, salicylic acid and adapalene, and none of them should be layered with this toner on the same night. Where it fits is a resilient, oily face in hot weather that wants a fragrance-free, drying first step.

Formula

Key ingredients

  1. Dipotassium Glycyrrhizate

    The first of two registered anti-inflammatory actives, licorice's glycyrrhizin salt, approved in Japan for preventing acne and rough skin; it is the reason the lotion is a quasi-drug and the ingredient doing the calming that the adlay on the front gets credit for.

    Not yet assessed
  2. Epsilon-Aminocaproic Acid

    The second active, an antifibrinolytic amino acid related to tranexamic acid that Japanese quasi-drugs use as an anti-inflammatory for irritated skin; a pharmacy ingredient with little Western cosmetic profile and a specific, modest job here.

    Not yet assessed
  3. Coix Lacryma-Jobi (Job's Tears) Seed Extract

    The adlay, or hatomugi, that names the product: Japan's favourite folk remedy for rough, bumpy skin, with polysaccharides that soften and a long kampo tradition. Its role is humectant and cultural; the registered actives carry the acne claim.

    Not yet assessed
  4. Houttuynia Cordata and Chamomile Extracts

    Two calming botanicals, fish mint with anti-inflammatory polysaccharides in mouse dermatitis models and chamomile with a long anti-irritant record, listed at extract level to support the actives on skin that is red and reactive.

    Not yet assessed
  5. Menthol and Camphor

    The cooling pair that gives the lotion its bracing, pore-tightening feel on a hot face and its faintly medicinal smell; a sensation of relief rather than a treatment, and the two ingredients that make this the wrong Gokujyun for a compromised barrier.

    Not yet assessed
  6. Alcohol Denat. with Sodium Hyaluronate and Squalane

    Two grades of ethanol carry the botanicals and evaporate to a fresh, quick-drying finish that oily skin likes, while a single hyaluronate and a trace of squalane keep it from feeling stripping; it is the least Hada Labo-like base the line makes, and deliberately so.

    Not yet assessed
Full ingredient list 16 ingredients ShowHide

Active Ingredients: Dipotassium Glycyrrhizate, Epsilon-Aminocaproic Acid. Other Ingredients (Japanese quasi-drug declaration, not in descending order): Coix Lacryma-Jobi (Job's Tears) Seed Extract, Houttuynia Cordata Extract, Chamomilla Recutita (Matricaria) Flower Extract, Sodium Hyaluronate, Squalane, Camphor, Butylene Glycol, Triethylhexanoin, Menthol, PEG-40 Hydrogenated Castor Oil, Sorbitan Sesquioleate, Disodium EDTA, Alcohol, Alcohol Denat.

Safety & formulation facts

  • Pregnancy safe
  • Fragrance free
  • Not alcohol free
  • Not oil free
  • Silicone free
  • Paraben free
  • Sulfate free
  • Not cruelty free
  • Not vegan
  • Not fungal-acne safe
Potential irritants AlcoholAlcohol Denat.MentholCamphor
Common allergens Chamomilla Recutita (Matricaria) Flower Extract
Compatibility

Skin types & routine

Routine step toner
Time of day Morning & night
Best season summer
Finish matte, fast-absorbing, lightweight

Layering

Pat it on after cleansing as the first step, then follow with a light gel or milk; on oily skin in summer it can be the only hydrating step before sunscreen, and it should not be layered with a retinoid or acid on the same night given the alcohol and menthol.

When to expect results

A cool, tightened, refreshed feel immediately. The anti-inflammatory actives calm redness and reduce the frequency of small breakouts over two to four weeks of twice-daily use; texture smooths as oiliness settles. It prevents rather than treats, so existing spots need a separate product.

Pairs well with niacinamidehyaluronic-acidsunscreen
Don't combine with retinolglycolic-acidbenzoyl-peroxide

A routine built around it

Morning

  1. Gel cleanser
  2. Hada Labo Gokujyun Adlay Trouble Care Skin Conditioning Lotionthis product
  3. Light gel moisturiser
  4. Sunscreen SPF 50

Night

  1. Cleansing oil
  2. Gel cleanser
  3. Hada Labo Gokujyun Adlay Trouble Care Skin Conditioning Lotionthis product
  4. Niacinamide serum
  5. Light moisturiser
Guidance

How to use it, and who it's for

How to use

After cleansing, morning and evening, pour a generous amount into the palm and press it over the face, patting rather than rubbing; it cools, flashes off and leaves a clean, tightened feel within a minute. Follow with a light gel or milk, and in the morning with sunscreen. Keep it off the eye contour and off any patch that is broken, freshly exfoliated or sunburnt, where the alcohol and menthol will sting. Do not use it on the same night as a retinoid, an acid or benzoyl peroxide. Give it three to four weeks to judge the effect on small breakouts, and if the first splash stings rather than cools, take that as the verdict.

Is it worth the price?

Thirteen dollars and eighty-five cents for 170 millilitres, with a refill pouch cheaper still, is pharmacy pricing for a quasi-drug toner with two registered actives, and a generous twice-daily splash lasts about two months, so a year of use costs well under a hundred dollars. For oily, breakout-prone skin that is honest value: no Western drugstore toner offers this pairing of anti-inflammatories at the price. For anyone outside that skin type the value is nil, since the alcohol base will drive them to buy a second product to undo it. Rohto's pharmaceutical manufacturing and the formula's decade-plus stability make it a low-risk purchase for the right buyer. Bottle and refill formats are sold.

Who should buy it

Oily and combination skin, especially in hot, humid weather, that wants a fragrance-free medicated first step with two real anti-inflammatory actives and a cooling, drying finish at a pharmacy price. It suits teenagers and adults with frequent small breakouts who find the standard Gokujyun lotion too rich.

Who should skip it

Dry, sensitive, rosacea-prone, eczema-prone or barrier-compromised skin, for whom alcohol, menthol and camphor are the wrong trio at any price, and anyone using a retinoid or acid who cannot alternate nights. Anyone with existing spots to clear should buy a salicylic acid or benzoyl peroxide product instead of, or in addition to, this preventive.

Ready to try it?Hada Labo Gokujyun Adlay Trouble Care Skin Conditioning Lotion · $13.85 · 170 ml / 5.7 fl oz
Details

The product, in detail

Texture
A thin, watery, completely fluid lotion that spreads instantly, cools on contact and flashes off to a fresh, dry, slightly tightened finish.
Scent
No added fragrance, but a distinct medicinal note of menthol, camphor and ethanol on application that fades within a minute.
Packaging
A tall, soft plastic bottle in the Gokujyun Trouble Care line's mint green with white and gold lettering, a matching green screw cap and a narrow spout; a refill pouch is sold alongside.
How long it lasts
About two months at a generous twice-daily splash; three at once a day.
Once opened
Use within 12 months · track your toss-by date →
Size
170 ml / 5.7 fl oz · other sizes available
Made in
Japan
Certifications
Japanese quasi-drug (医薬部外品) registration

What the first two weeks feel like

The first splash is bracing: a cold menthol rush, a faint camphor smell and a tight, clean feel as the alcohol evaporates, all within a minute. Oily skin reads it as relief. Anything dry, freshly exfoliated or already irritated reads it as a sting, and that reaction on day one is the honest guide to whether to continue.

The story behind it

Why it exists

Rohto added a medicated skin conditioner to the Gokujyun line in the early 2010s to give the hyaluronic-acid brand an answer for oily and acne-prone customers who found the flagship lotion too rich, borrowing the adlay that Japanese pharmacies have sold for rough skin for generations and pairing it with two quasi-drug anti-inflammatories. It has stayed largely unchanged since, sold with a refill pouch, and import retailers market it as a trouble-care lotion for problem skin.

About Hada Labo Legacy Brand (20+ years)

Hada Labo is the skincare arm of Rohto Pharmaceutical, launched in 2004 around a stripped-down hyaluronic lotion that became a Japanese pharmacy fixture. Rohto registers medicated products like this one as quasi-drugs, which fixes the dose of two ministry-approved anti-inflammatory actives; that is a regulatory guarantee on the actives, not an independent trial of the finished lotion.

Brand founded 2004

Myth vs. reality

What people get wrong about it

MythThe adlay extract is what prevents acne in this lotion.

RealityAdlay, or Job's tears, is a traditional Japanese remedy for rough skin and a humectant here; the acne-and-rough-skin claim rests on the two registered actives, dipotassium glycyrrhizate and epsilon-aminocaproic acid, which are the anti-inflammatories the quasi-drug approval covers. The adlay is the name and the tradition.

MythBecause it is a Hada Labo product, it is as gentle as the Gokujyun hyaluronic lotion.

RealityIt is the least gentle product in the line by design: two grades of alcohol, menthol and camphor give the cooling, drying, tightening feel that oily skin wants and that dry, sensitive or barrier-compromised skin will find stinging. The Gokujyun name signals the brand, not the formula.

FAQ

Questions people ask

What are the active ingredients in the Hada Labo Adlay Skin Conditioning Lotion?

Two registered quasi-drug actives: dipotassium glycyrrhizate, the anti-inflammatory salt of licorice's glycyrrhizin, and epsilon-aminocaproic acid, an antifibrinolytic amino acid Japanese pharmacies use to calm irritated skin. Together they are approved for preventing acne and rough skin; the adlay, fish mint and chamomile extracts are supporting botanicals.

Does the Hada Labo Adlay lotion contain alcohol?

Yes, two grades of ethanol are listed, along with menthol and camphor. They give the lotion its cooling, quick-drying, pore-tightening feel and its faintly medicinal smell, and they are the reason it suits oily skin in summer and stings on dry, sensitive or irritated skin.

Is the Hada Labo Adlay Skin Conditioner good for acne?

It is a preventive rather than a treatment. The two anti-inflammatory actives reduce redness and the frequency of small breakouts on oily skin over a few weeks, and the alcohol base keeps the surface clean and dry. It does not unclog pores or clear existing spots, for which salicylic acid, benzoyl peroxide or adapalene are the tools.

How is the Adlay Skin Conditioner different from the regular Gokujyun Hyaluronic Lotion?

Almost entirely. The hyaluronic lotion is a thick, alcohol-free humectant water for dry and sensitive skin; the skin conditioner is a thin, alcohol-carried medicated toner with two anti-inflammatory actives, menthol and camphor for oily, breakout-prone skin. They share the Gokujyun name and a single hyaluronate, nothing else.

Can I use the Hada Labo Adlay lotion on sensitive skin?

It is not the Hada Labo for that. Alcohol, menthol and camphor together are a recipe for stinging on reactive, rosacea-prone or barrier-compromised skin, whatever the calming actives do. Sensitive skin should use the alcohol-free Gokujyun hyaluronic lotion and treat breakouts with a targeted product.

Is the Hada Labo Skin Conditioner fragrance-free?

It has no added fragrance or colourant, as Rohto states, but it is not scentless: menthol, camphor and ethanol give it a distinct medicinal smell on application that fades within a minute. Anyone who finds pharmacy-style cooling products off-putting will notice it.

Reviews

What shoppers tend to say

Recurring themes our editors read across retailer reviews — summaries in our words, not quotations, and not a substitute for a patch test.

Common praise

  • Cooling menthol feel that tightens pores after a hot shower
  • Keeps small breakouts down when used daily
  • Cheap enough to splash on generously

Common complaints

  • Alcohol and menthol sting on dry or irritated skin
  • Medicinal scent is not for everyone
  • Not hydrating enough alone in winter
Notable endorsementsRegistered quasi-drug in Japan with two approved anti-inflammatory actives
Next stepCheck it against what you already useClashes, spacing and the right order, with everything on your shelf.